Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Wolff-Parkinson-White syndrome
ADR ID BADD_A07836
ADR Hierarchy
02      Cardiac disorders
02.03      Cardiac arrhythmias
02.03.01      Cardiac conduction disorders
02.03.01.016      Wolff-Parkinson-White syndrome
Description A form of ventricular pre-excitation characterized by a short PR interval and a long QRS interval with a delta wave. In this syndrome, atrial impulses are abnormally conducted to the HEART VENTRICLES via an ACCESSORY CONDUCTING PATHWAY that is located between the wall of the right or left atria and the ventricles, also known as a BUNDLE OF KENT. The inherited form can be caused by mutation of PRKAG2 gene encoding a gamma-2 regulatory subunit of AMP-activated protein kinase. [MeSH]
MedDRA Code 10048015
MeSH ID D014927; D011226
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Wolff-Parkinson-White syndrome | WPW syndrome | Wolff-Parkinson-White syndrome acquired | Pre-excitation syndrome | Wolff-Parkinson-White Syndrome | Syndrome, Wolff-Parkinson-White | Wolff Parkinson White Syndrome | Auriculoventricular Accessory Pathway Syndrome | WPW Syndrome | Syndrome, WPW | Ventricular Pre-Excitation with Arrhythmia | Wolf-Parkinson-White Syndrome | Syndrome, Wolf-Parkinson-White | Wolf Parkinson White Syndrome | Anomalous Ventricular Excitation Syndrome | False Bundle-Branch Block Syndrome
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00115Amiodarone0.000269%
BADD_D00165Aripiprazole0.000159%
BADD_D00293Brexpiprazole0.000131%
BADD_D00511Clozapine0.001223%
BADD_D00668Digoxin0.000211%
BADD_D00680Dimethyl fumarate0.000400%
BADD_D01119Ibrutinib0.000112%
BADD_D01431Methylphenidate0.000041%
BADD_D01679Paroxetine0.000064%
BADD_D01867Propranolol0.000080%
BADD_D01951Risperidone0.000667%
BADD_D02464Fingolimod0.000241%
The 1th Page    1    Total 1 Pages