Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Malignant pleural effusion
ADR ID BADD_A07394
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.32      Neoplasm related morbidities
16.32.03      Oncologic complications and emergencies
16.32.03.014      Malignant pleural effusion
22      Respiratory, thoracic and mediastinal disorders
22.05      Pleural disorders
22.05.04      Pleural neoplasms
22.05.04.001      Malignant pleural effusion
Description Presence of fluid in the PLEURAL CAVITY as a complication of malignant disease. Malignant pleural effusions often contain actual malignant cells. [MeSH]
MedDRA Code 10026673
MeSH ID D016066
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Malignant pleural effusion | Malignant pleurisy | Carcinomatous pleurisy | Pleural Effusion, Malignant | Effusion, Malignant Pleural | Effusions, Malignant Pleural | Malignant Pleural Effusion | Malignant Pleural Effusions | Pleural Effusions, Malignant
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00047Afatinib0.000504%
BADD_D00142Anastrozole0.000238%
BADD_D00151Apixaban0.000065%
BADD_D00330Cabozantinib0.000168%
BADD_D00349Capecitabine0.000168%
BADD_D00364Carboplatin0.000112%
BADD_D00414Ceritinib0.000224%
BADD_D00535Crizotinib0.000168%
BADD_D00563Dabigatran0.000245%
BADD_D00589Dasatinib0.000112%
BADD_D00775Enzalutamide0.000334%
BADD_D00798Eribulin0.000168%
BADD_D00800Erlotinib0.000448%
BADD_D00858Everolimus0.000306%
BADD_D01008Gefitinib0.000168%
BADD_D01096Hydromorphone--
BADD_D01119Ibrutinib0.000112%
BADD_D01254Lenvatinib0.000392%
BADD_D01257Letrozole0.000790%
BADD_D01258Leucovorin0.001239%
BADD_D01378Memantine0.000121%
BADD_D01629Osimertinib0.000504%
BADD_D01653Paclitaxel0.000168%
BADD_D01654Palbociclib0.000280%
BADD_D01687Pazopanib0.000224%
BADD_D01798Pomalidomide0.000362%
BADD_D01922Regorafenib0.000112%
BADD_D02029Sitagliptin0.000080%
BADD_D02058Sorafenib0.000280%
BADD_D02100Sunitinib0.000224%
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