Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Acute kidney injury
ADR ID BADD_A06560
ADR Hierarchy
20      Renal and urinary disorders
20.01      Renal disorders (excl nephropathies)
20.01.03      Renal failure and impairment
20.01.03.016      Acute kidney injury
Description A disorder characterized by the acute loss of renal function (within 2 weeks) and is traditionally classified as pre-renal (low blood flow into kidney), renal (kidney damage) and post-renal causes (ureteral or bladder outflow obstruction). [CTCAE] Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions. | Conditions in which the function of KIDNEYS deteriorates suddenly in a matter of days or even hours. It is characterized by the sudden drop in GLOMERULAR FILTRATION RATE. [MeSH]
MedDRA Code 10069339
MeSH ID D058186
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Acute kidney failure | Acute on chronic renal failure | Acute prerenal failure | Acute renal failure | Acute renal failure following labor and delivery | Acute renal failure following labor and delivery, postpartum condition or complication | Acute renal failure following labor and delivery, unspecified as to episode of care | Acute renal failure following labour and delivery | Acute renal failure with delivery, with mention of postpartum complication | Acute renal failure with lesion of renal cortical necrosis | Acute renal failure with lesion of renal medullary (papillary) necrosis | Acute renal failure with lesion of tubular necrosis | Acute renal failure with other specified pathological lesion in kidney | Acute renal failure, unspecified | ARF | Azotemia prerenal | Failure kidney acute | Kidney failure acute | Renal failure acute | Renal failure acute hypotensive | Renal failure acute ischaemic | Renal failure acute ischemic | Renal failure acute on chronic | Renal failure acute uratic | Renal shutdown acute | Shutdown renal | Acute renal insufficiency | Rhabdomyolysis-induced renal failure | Azotaemia prerenal | Acute oliguric renal failure | Acute kidney injury | Stage 1 acute kidney injury | Stage 2 acute kidney injury | Stage 3 acute kidney injury | Acute nonoliguric renal failure | Acute prerenal insufficiency | Acute Kidney Injury | Acute Kidney Injuries | Kidney Injuries, Acute | Kidney Injury, Acute | Acute Renal Injury | Acute Renal Injuries | Renal Injuries, Acute | Renal Injury, Acute | Renal Insufficiency, Acute | Acute Renal Insufficiencies | Renal Insufficiencies, Acute | Acute Renal Insufficiency | Kidney Insufficiency, Acute | Acute Kidney Insufficiencies | Kidney Insufficiencies, Acute | Acute Kidney Insufficiency | Kidney Failure, Acute | Acute Kidney Failures | Kidney Failures, Acute | Acute Renal Failure | Acute Renal Failures | Renal Failures, Acute | Renal Failure, Acute | Acute Kidney Failure
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00178Atenolol0.000417%
BADD_D00182Atorvastatin calcium--
BADD_D00186Atovaquone0.000283%
BADD_D00193Axitinib--
BADD_D00194Azacitidine0.002630%
BADD_D00195Azathioprine0.003916%
BADD_D00201Azilsartan kamedoxomil0.000039%
BADD_D00203Azithromycin--
BADD_D00204Azithromycin dihydrate--
BADD_D00205Azithromycin monohydrate--
BADD_D00223Belatacept--
BADD_D00229Benazeprilat-
BADD_D00230Bendamustine0.001119%
BADD_D00231Bendamustine hydrochloride--
BADD_D00270Bezafibrate--
BADD_D00271Bicalutamide0.012655%
BADD_D00277Bisoprolol0.011460%
BADD_D00284Bortezomib--
BADD_D00286Bosutinib--
BADD_D00287Bosutinib monohydrate--
BADD_D00307Bumetanide0.002034%
BADD_D00312Bupropion0.000432%
BADD_D00318Busulfan0.000280%
BADD_D00328Cabazitaxel--
BADD_D00330Cabozantinib--
BADD_D00332Caffeine0.000139%
BADD_D00337Calcitriol0.000893%
BADD_D00344Canagliflozin0.009175%
BADD_D00347Candesartan cilexetil0.021867%
BADD_D00349Capecitabine0.005451%
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