Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Sphincter of Oddi dysfunction
ADR ID BADD_A06386
ADR Hierarchy
07      Gastrointestinal disorders
07.18      Exocrine pancreas conditions
07.18.02      Pancreatic disorders NEC
07.18.02.002      Sphincter of Oddi dysfunction
09      Hepatobiliary disorders
09.02      Bile duct disorders
09.02.02      Obstructive bile duct disorders (excl neoplasms)
09.02.02.004      Sphincter of Oddi dysfunction
Description Organic or functional motility disorder involving the SPHINCTER OF ODDI and associated with biliary COLIC. Pathological changes are most often seen in the COMMON BILE DUCT sphincter, and less commonly the PANCREATIC DUCT sphincter. [MeSH]
MedDRA Code 10066424
MeSH ID D046628
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Oddi's sphincter constriction | Oddi's sphincter spasm | Spasm of sphincter of Oddi | Sphincter of Oddi dysfunction | Sphincter of Oddi Dysfunction | Sphincter of Oddi Stenosis | Sphincter of Oddi Dyskinesia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00151Apixaban0.000065%
BADD_D00516Codeine0.000686%
BADD_D00761Eluxadoline0.000396%
BADD_D00778Ephedrine sulfate--
BADD_D01498Morphine0.000557%
BADD_D01645Oxycodone0.000021%
BADD_D02139Tegaserod maleate--
BADD_D02140Tegaserode--
BADD_D02254Tramadol0.000014%
BADD_D02428Loperamide0.000338%
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