Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Thyrotoxic crisis
ADR ID BADD_A04306
ADR Hierarchy
14      Metabolism and nutrition disorders
14.11      Metabolism disorders NEC
14.11.01      Metabolic disorders NEC
14.11.01.016      Thyrotoxic crisis
06      Eye disorders
06.09      Ocular structural change, deposit and degeneration NEC
06.09.04      Structural change, deposit and degeneration of eye NEC
06.09.04.004      Thyrotoxic crisis
19      Psychiatric disorders
19.07      Psychiatric disorders NEC
19.07.03      Mental disorders due to a general medical condition NEC
19.07.03.006      Thyrotoxic crisis
05      Endocrine disorders
05.02      Thyroid gland disorders
05.02.02      Thyroid hyperfunction disorders
05.02.02.004      Thyrotoxic crisis
Description A dangerous life-threatening hypermetabolic condition characterized by high FEVER and dysfunction of the cardiovascular, the nervous, and the gastrointestinal systems. [MeSH]
MedDRA Code 10043786
MeSH ID D013958
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Crisis thyroid | Thyroid crisis | Thyroid storm | Thyrotoxic crisis | Thyrotoxicosis from ectopic thyroid nodule with mention of thyrotoxic crisis or storm | Thyrotoxicosis of other specified origin with mention of thyrotoxic crisis or storm | Thyrotoxicosis without mention of goiter or other cause, with mention of thyrotoxic crisis or storm | Toxic diffuse goiter with mention of thyrotoxic crisis or storm | Toxic diffuse goitre with mention of thyrotoxic crisis or storm | Toxic multinodular goiter with mention of thyrotoxic crisis or storm | Toxic nodular goiter, unspecified type, with mention of thyrotoxic crisis or storm | Toxic uninodular goiter with mention of thyrotoxic crisis or storm | Thyroid Crisis | Crisis, Thyroid | Thyrotoxic Storm | Storm, Thyrotoxic | Thyrotoxic Crisis | Crisis, Thyrotoxic | Thyroid Storm | Storm, Thyroid
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00115Amiodarone0.001212%
BADD_D00193Axitinib0.000112%
BADD_D00365Carboprost--
BADD_D00366Carboprost tromethamine--
BADD_D00545Cyclobenzaprine0.000016%
BADD_D00653Diclofenac0.000026%
BADD_D00680Dimethyl fumarate0.000600%
BADD_D00782Epinephrine0.000121%
BADD_D00816Esomeprazole magnesium--
BADD_D00817Esomeprazole sodium--
BADD_D01095Hydrogen iodide--
BADD_D01111Hydroxyzine0.000056%
BADD_D01119Ibrutinib0.000280%
BADD_D01180Iohexol0.010670%
BADD_D01182Iopromide--
BADD_D01285Levothyroxine0.000005%
BADD_D01303Lithium carbonate0.001606%
BADD_D01304Lithium cation0.000576%
BADD_D01414Methimazole0.001719%
BADD_D01834Prednisone0.000013%
BADD_D01869Propylthiouracil0.023510%
BADD_D02373Warfarin0.000028%
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