Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Iohexol
Drug ID BADD_D01180
Description Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Indications and Usage Iohexol ia used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures.
Marketing Status approved
ATC Code V08AB02
DrugBank ID DB01362
KEGG ID D01817
MeSH ID D007472
PubChem ID 3730
TTD Drug ID D02BLO
NDC Product Code 43228-100; 0407-1413; 71806-141; 0407-1414; 0407-1416; 0407-1415; 0407-1401; 0407-1411; 0407-1412; 65072-0801; 54702-501
UNII 4419T9MX03
Synonyms Iohexol | Iohexol 350 | Nycodenz | Compound 545 | Exypaque | Omnipaque
Chemical Information
Molecular Formula C19H26I3N3O9
CAS Registry Number 66108-95-0
SMILES CC(=O)N(CC(CO)O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Acute pulmonary oedema02.05.02.004; 22.01.03.0050.021340%-
Acute respiratory failure14.01.04.004; 22.02.06.0010.014227%-
Agitation17.02.05.012; 19.06.02.001--
Air embolism12.02.05.008; 24.01.01.0010.024897%-
Altered state of consciousness17.02.04.001; 19.07.01.0030.024897%-
Amaurosis06.02.10.0010.010670%-
Amblyopia06.02.01.001---
Amnesia17.03.02.001; 19.20.01.001--
Amylase increased13.05.01.009--
Anaphylactic reaction10.01.07.001; 24.06.03.0060.428226%
Anaphylactic shock10.01.07.002; 24.06.02.0040.234742%-
Anaphylactoid reaction10.01.07.003; 24.06.03.0070.064020%-
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.0010.207000%-
Anuria20.01.03.0020.007113%-
Anxiety19.06.02.002--
Aortic aneurysm rupture24.02.03.0030.007113%-
Aphasia17.02.03.001; 19.21.01.0010.053350%
Aphonia17.02.08.009; 19.19.01.002; 22.12.03.0010.014227%
Apnoea22.02.01.0010.029876%
Areflexia17.02.01.001---
Arrhythmia02.03.02.001---
Arterial spasm24.04.02.011---
Arterial thrombosis24.01.01.002---
Arteriospasm coronary02.02.02.005; 12.02.01.031; 24.04.04.0050.010670%-
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Asphyxia12.01.08.011; 22.02.02.0010.014227%-
Aspiration22.02.07.0070.021340%
Asterixis09.01.03.004; 17.01.06.001---
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ADReCS-Target
Drug Name ADR Term Target
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