Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Stomatitis necrotising
ADR ID BADD_A04159
ADR Hierarchy
07      Gastrointestinal disorders
07.05      Oral soft tissue conditions
07.05.06      Stomatitis and ulceration
07.05.06.006      Stomatitis necrotising
Description A severe gangrenous process occurring predominantly in debilitated and malnourished children, especially in underdeveloped countries. It typically begins as a small vesicle or ulcer on the gingiva that rapidly becomes necrotic and spreads to produce extensive destruction of the buccal and labial mucosa and tissues of the face, which may result in severe disfigurement and even death. Various bacteria have been implicated in the etiology. (Dorland, 27th ed) [MeSH]
MedDRA Code 10042135
MeSH ID D009625
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Cancrum oris | Mouth necrosis | Necrosis mouth | Noma | Stomatitis necrotising | Stomatitis necrotizing | Nomas | Stomatitis, Gangrenous | Gangrenous Stomatitides | Gangrenous Stomatitis | Stomatitides, Gangrenous | Cancrum Oris
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01231Ketoprofen--
BADD_D01275Levofloxacin0.000042%
BADD_D02018Sildenafil0.000107%
BADD_D02149Temoporfin--
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