Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Spinal osteoarthritis
ADR ID BADD_A04130
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.01      Joint disorders
15.01.04      Osteoarthropathies
15.01.04.003      Spinal osteoarthritis
Description A degenerative joint disease involving the SPINE. It is characterized by progressive deterioration of the spinal articular cartilage (CARTILAGE, ARTICULAR), usually with hardening of the subchondral bone and outgrowth of bone spurs (OSTEOPHYTE). [MeSH]
MedDRA Code 10041591
MeSH ID D055013; D055009
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Cervical spine degeneration | Cervical spondylosis | Cervical spondylosis without myelopathy | Degenerative arthritis spine | Hyperostotic spondylosis | Inflammatory spondylopathies in diseases classified elsewhere | Lumbar spine degeneration | Lumbar spondylosis | Lumbo-sacral spondylosis | Lumbosacral spondylosis without myelopathy | O/A spine | OA lumbar spine | OA neck | OA spine | Osteoarthritis of neck | Osteoarthritis of cervical spine | Osteoarthritis of lumbar spine | Osteoarthritis of thoracic spine | Osteoarthritis spinal | Other inflammatory spondylopathies | Other spondylosis and allied disorders | Sacro-iliac spondylosis | Spinal osteoarthritis | Spondylosis | Spondylosis and allied disorders | Spondylosis and allied disorders, other | Spondylosis NOS | Spondylosis of unspecified site | Spondylosis of unspecified site without mention of myelopathy | Thoracic spine degeneration | Thoracic spondylosis | Thoracic spondylosis without myelopathy | Uncarthrosis | Spondyloarthrosis | Spondylosis deformans | Hemispherical spondylosclerosis | Spondylosis aggravated | Degenerative spine disease | Osteoarthritis, Spine | Spinal Osteoarthritis | Osteoarthritis, Spinal | Spine Osteoarthritis | Lumbar Osteoarthritis | Osteoarthritis, Lumbar
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00044Adefovir dipivoxil0.000847%
BADD_D00066Alendronic acid0.003258%
BADD_D00165Aripiprazole0.000174%
BADD_D00330Cabozantinib0.000112%
BADD_D00347Candesartan cilexetil0.000841%
BADD_D00410Celecoxib0.000209%
BADD_D00504Clopidogrel0.000032%
BADD_D00608Denosumab--
BADD_D00648Diazepam0.000050%
BADD_D00680Dimethyl fumarate--
BADD_D00898Finasteride0.000279%
BADD_D00981Gabapentin0.000039%
BADD_D01119Ibrutinib0.000168%
BADD_D01245Lansoprazole0.000099%
BADD_D01257Letrozole0.000263%
BADD_D01258Leucovorin0.001239%
BADD_D01260Leuprolide acetate0.001434%
BADD_D01261Leuprolide monoacetate--
BADD_D01318Lorazepam0.000031%
BADD_D01418Methotrexate--
BADD_D01567Nilotinib0.000280%
BADD_D01817Pramipexole--
BADD_D01818Pramipexole dihydrochloride--
BADD_D01831Prednisolone0.000052%
BADD_D01834Prednisone--
BADD_D01835Pregabalin0.000519%
BADD_D01909Ramipril0.000093%
BADD_D01971Rosuvastatin0.000038%
BADD_D02026Simvastatin0.000007%
BADD_D02029Sitagliptin0.000913%
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