Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Rhabdomyolysis
ADR ID BADD_A03877
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.05      Muscle disorders
15.05.05      Myopathies
15.05.05.002      Rhabdomyolysis
Description A disorder characterized by the breakdown of muscle tissue resulting in the release of muscle fiber contents into the bloodstream. [CTCAE] Necrosis or disintegration of skeletal muscle often followed by myoglobinuria. [MeSH]
MedDRA Code 10039020
MeSH ID D012206
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Muscle dissolution | Rhabdomyolysis | Rhabdomyolyses
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02195Theophylline--
BADD_D02214Ticagrelor0.002720%
BADD_D02217Tigecycline0.000049%
BADD_D02227Tipranavir disodium--
BADD_D02230Tizanidine0.000115%
BADD_D02241Tolcapone--
BADD_D02246Tolvaptan--
BADD_D02253Trabectedin0.002183%
BADD_D02254Tramadol0.000174%
BADD_D02257Trametinib--
BADD_D02258Trametinib dimethyl sulfoxide--
BADD_D02270Tretinoin0.000107%
BADD_D02277Triazolam0.000403%
BADD_D02279Trientine--
BADD_D02280Trientine hydrochloride--
BADD_D02305Trospium--
BADD_D02306Trospium chloride--
BADD_D02329Valproic acid0.001098%
BADD_D02331Valsartan0.000317%
BADD_D02346Venlafaxine0.000354%
BADD_D02347Venlafaxine hydrochloride--
BADD_D02365Vismodegib0.000336%
BADD_D02369Voriconazole0.066798%
BADD_D02381Ziconotide--
BADD_D02382Ziconotide acetate--
BADD_D02383Zidovudine--
BADD_D02389Ziprasidone hydrochloride--
BADD_D02392Zoledronic acid0.022044%
BADD_D02394Zolpidem0.000484%
BADD_D02396Zonisamide--
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ADReCS-Target
ADR Term Drug Name Target