Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Purpura
ADR ID BADD_A03668
ADR Hierarchy
01      Blood and lymphatic system disorders
01.01      Coagulopathies and bleeding diatheses (excl thrombocytopenic)
01.01.04      Purpuras (excl thrombocytopenic)
01.01.04.003      Purpura
23      Skin and subcutaneous tissue disorders
23.06      Skin vascular abnormalities
23.06.01      Purpura and related conditions
23.06.01.004      Purpura
24      Vascular disorders
24.07      Vascular haemorrhagic disorders
24.07.06      Bruising, ecchymosis and purpura
24.07.06.005      Purpura
Description A disorder characterized by hemorrhagic areas of the skin and mucous membrane. Newer lesions appear reddish in color. Older lesions are usually a darker purple color and eventually become a brownish-yellow color. [CTCAE] Purplish or brownish red discoloration, easily visible through the epidermis, caused by hemorrhage into the tissues. When the size of the discolorization is >2-3 cm it is generally called Ecchymoses (ECCHYMOSIS). | Pinhead size (3 mm) skin discolorization due to hemorrhage. [MeSH]
MedDRA Code 10037549
MeSH ID D011693
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Dermatitis haemorrhagic | Dermatitis hemorrhagic | Haemolytic type rash | Haemorrhage purpuric | Idiopathic purpura | Purpura | Purpura NOS | Purpuric rash | Rash haemorrhagic | Rash hemorrhagic | Rash purpitic | Rash purpuric | Purpura symptomatica | Hemorrhage purpuric | Hemolytic type rash | Wet purpura | Dry purpura | Retiform purpura | Mechanical purpura | Purpuras | Petechiae
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01521Nalidixic acid--
BADD_D01527Naltrexone--
BADD_D01533Naproxen--
BADD_D01534Naproxen sodium--
BADD_D01535Naratriptan--
BADD_D01536Naratriptan hydrochloride--
BADD_D01566Nifedipine--
BADD_D01576Nitrofurantoin--
BADD_D01585Norethindrone--
BADD_D01588Nortriptyline--
BADD_D01589Nortriptyline hydrochloride--
BADD_D01598Ofloxacin--
BADD_D01602Olmesartan0.000157%
BADD_D01609Omacetaxine mepesuccinate--
BADD_D01614Omeprazole--
BADD_D01615Omeprazole magnesium--
BADD_D01629Osimertinib0.000392%
BADD_D01633Oxaliplatin--
BADD_D01635Oxaprozin--
BADD_D01637Oxcarbazepine--
BADD_D01645Oxycodone--
BADD_D01668Pantoprazole0.000123%
BADD_D01679Paroxetine0.000043%
BADD_D01680Paroxetine hydrochloride--
BADD_D01681Paroxetine hydrochloride hemihydrate--
BADD_D01682Paroxetine impurity a--
BADD_D01683Paroxetine mesylate--
BADD_D01687Pazopanib0.000336%
BADD_D01701Pemetrexed0.000168%
BADD_D01707Penbutolol sulfate--
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