Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Porphyria
ADR ID BADD_A03510
ADR Hierarchy
14      Metabolism and nutrition disorders
14.14      Inborn errors of metabolism
14.14.01      Inborn errors of porphyrin metabolism
14.14.01.001      Porphyria
03      Congenital, familial and genetic disorders
03.08      Metabolic and nutritional disorders congenital
03.08.01      Inborn errors of porphyrin metabolism
03.08.01.001      Porphyria
Description A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues. [MeSH]
MedDRA Code 10036181
MeSH ID D011164
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Porphyria | Porphyria NOS | Porphyria type syndrome | Porphyria aggravated | Porphyrias | Porphyrin Disorder | Disorder, Porphyrin | Disorders, Porphyrin | Porphyrin Disorders
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00528Conjugated estrogens--
BADD_D00787Epoetin alfa--
BADD_D00808Erythropoietin--
BADD_D00820Esterified estrogens--
BADD_D00821Estradiol--
BADD_D00822Estradiol acetate--
BADD_D00823Estradiol cypionate--
BADD_D00824Estradiol hemihydrate--
BADD_D00825Estradiol valerate--
BADD_D00831Estrogens--
BADD_D00832Estrogens conjugated synthetic a--
BADD_D00833Estrogens conjugated synthetic b--
BADD_D00836Estropipate--
BADD_D00844Ethinyl estradiol--
BADD_D00951Fluvoxamine maleate--
BADD_D01104Hydroxychloroquine sulfate--
BADD_D01366Medroxyprogesterone acetate--
BADD_D01390Meprobamate--
BADD_D01442Metoclopramide--
BADD_D01443Metoclopramide hydrochloride--
BADD_D01679Paroxetine--
BADD_D01680Paroxetine hydrochloride--
BADD_D01681Paroxetine hydrochloride hemihydrate--
BADD_D01683Paroxetine mesylate--
BADD_D01880Pyrazinamide--
BADD_D01937Rifapentine--
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ADReCS-Target
ADR Term Drug Name Target