Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Palmar-plantar erythrodysaesthesia syndrome
ADR ID BADD_A03260
ADR Hierarchy
23      Skin and subcutaneous tissue disorders
23.03      Epidermal and dermal conditions
23.03.05      Dermatitis ascribed to specific agent
23.03.05.009      Palmar-plantar erythrodysaesthesia syndrome
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.07      Sensory abnormalities NEC
17.02.07.009      Palmar-plantar erythrodysaesthesia syndrome
Description Not Available
MedDRA Code 10033553
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Hand and foot syndrome | Hand-and-foot syndrome | Palmar-plantar erythrodysaesth. | Palmar-plantar erythrodysaesthesia syndrome | Hand and foot syndrome secondary to chemotherapy | Palmar-plantar erythrodysesthesia syndrome | Palmar-plantar erythema | Hand and foot skin reaction | Acral erythema | Genital erythrodysesthesia | Genital erythrodysaesthesia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01195Irinotecan0.000302%
BADD_D01196Irinotecan hydrochloride--
BADD_D01222Ixabepilone--
BADD_D01248Lapatinib0.003280%
BADD_D01254Lenvatinib0.015480%
BADD_D01258Leucovorin0.002726%
BADD_D01393Meropenem0.000073%
BADD_D01511Nabumetone0.000589%
BADD_D01566Nifedipine--
BADD_D01567Nilotinib--
BADD_D01633Oxaliplatin--
BADD_D01653Paclitaxel0.003738%
BADD_D01655Palifermin--
BADD_D01687Pazopanib0.008451%
BADD_D01688Pazopanib hydrochloride--
BADD_D01804Posaconazole0.004728%
BADD_D01911Ramucirumab--
BADD_D01922Regorafenib0.043842%
BADD_D02058Sorafenib0.030691%
BADD_D02100Sunitinib0.041940%
BADD_D02101Sunitinib malate--
BADD_D02253Trabectedin0.000280%
BADD_D02258Trametinib dimethyl sulfoxide--
BADD_D02334Vandetanib0.000168%
BADD_D02344Vemurafenib0.002048%
BADD_D02506Erdafitinib0.000683%
BADD_D02531Avapritinib0.000246%
BADD_D02545Dacomitinib0.000112%
BADD_D02552Encorafenib0.000302%
BADD_D02591Ripretinib0.003358%
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ADReCS-Target
ADR Term Drug Name Target