Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Palifermin
Drug ID BADD_D01655
Description Palifermin is a recombinant human keratinocyte growth factor (KGF). It is 140 residues long, and is produced using E. coli. Palifermin was granted FDA approval on 15 December 2004.[L17933]
Indications and Usage For treatment of oral mucositis associated with chemotherapy and radiation therapy.
Marketing Status approved
ATC Code V03AF08
DrugBank ID DB00039
KEGG ID D05338
MeSH ID D051523
PubChem ID Not Available
TTD Drug ID D0O7GU
NDC Product Code 66658-112
UNII QMS40680K6
Synonyms Fibroblast Growth Factor 7 | Keratinocyte Growth Factor | Palifermin
Chemical Information
Molecular Formula Not Available
CAS Registry Number 162394-19-6
SMILES Not Available
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Amylase increased13.05.01.009--
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Arthralgia15.01.02.001--
Dysaesthesia17.02.06.003; 23.03.03.077--
Dysgeusia07.14.03.001; 17.02.07.003--
Erythema23.03.06.001---
Face oedema08.01.07.003; 10.01.05.002; 23.04.01.004--
Hyperaesthesia17.02.06.004; 23.03.03.080---
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hypoaesthesia17.02.06.023; 23.03.03.081---
Lipase increased13.05.01.003--
Oedema08.01.07.006; 14.05.06.010---
Oedema mouth07.05.04.001; 10.01.05.006; 23.04.01.008---
Oral mucosal discolouration07.05.05.007---
Pain08.01.08.004--
Palmar-plantar erythrodysaesthesia syndrome17.02.07.009; 23.03.05.009--
Paraesthesia17.02.06.005; 23.03.03.094--
Proteinuria20.02.01.011--
Pruritus23.03.12.001--
Pyrexia08.05.02.003--
Rash23.03.13.001---
Skin hyperpigmentation23.05.01.003--
Tongue discolouration07.14.02.006---
Tongue disorder07.14.01.002---
Antibody test positive13.06.03.001---
Vaginal oedema21.08.02.010---
Vulvovaginal erythema21.08.02.011; 23.03.06.017---
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