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ADR Term
ADReCS ID
MedDRA Code
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ADR Ontology
ADR Term
Osteosclerosis
ADR ID
BADD_A03226
ADR Hierarchy
15
Musculoskeletal and connective tissue disorders
15.02
Bone disorders (excl congenital and fractures)
15.02.04
Bone disorders NEC
15.02.04.012
Osteosclerosis
Description
An abnormal hardening or increased density of bone tissue. [MeSH]
MedDRA Code
10031298
MeSH ID
D010026
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Not Available
Synonym
Osteosclerosis | Vertebral sclerosis | Subchondral osteosclerosis | Osteoscleroses
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D00066
Alendronic acid
0.000383%
BADD_D00271
Bicalutamide
0.001406%
BADD_D00308
Bupivacaine
-
-
BADD_D01038
Goserelin
0.000501%
BADD_D01242
Lamivudine
0.001012%
BADD_D01257
Letrozole
0.000395%
BADD_D01654
Palbociclib
0.000112%
BADD_D01831
Prednisolone
0.000035%
BADD_D02029
Sitagliptin
0.000053%
BADD_D02154
Tenofovir
0.001939%
BADD_D02344
Vemurafenib
0.000112%
BADD_D02346
Venlafaxine
-
-
BADD_D02392
Zoledronic acid
0.011452%
BADD_D02586
Radium ra-223 dichloride
-
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