Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Osteosclerosis
ADR ID BADD_A03226
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.02      Bone disorders (excl congenital and fractures)
15.02.04      Bone disorders NEC
15.02.04.012      Osteosclerosis
Description An abnormal hardening or increased density of bone tissue. [MeSH]
MedDRA Code 10031298
MeSH ID D010026
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Osteosclerosis | Vertebral sclerosis | Subchondral osteosclerosis | Osteoscleroses
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000383%
BADD_D00271Bicalutamide0.001406%
BADD_D00308Bupivacaine--
BADD_D01038Goserelin0.000501%
BADD_D01242Lamivudine0.001012%
BADD_D01257Letrozole0.000395%
BADD_D01654Palbociclib0.000112%
BADD_D01831Prednisolone0.000035%
BADD_D02029Sitagliptin0.000053%
BADD_D02154Tenofovir0.001939%
BADD_D02344Vemurafenib0.000112%
BADD_D02346Venlafaxine--
BADD_D02392Zoledronic acid0.011452%
BADD_D02586Radium ra-223 dichloride-
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