Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Microangiopathic haemolytic anaemia
ADR ID BADD_A02770
ADR Hierarchy
24      Vascular disorders
24.03      Vascular disorders NEC
24.03.02      Non-site specific vascular disorders NEC
24.03.02.019      Microangiopathic haemolytic anaemia
01      Blood and lymphatic system disorders
01.06      Haemolyses and related conditions
01.06.02      Anaemias haemolytic mechanical factor
01.06.02.002      Microangiopathic haemolytic anaemia
Description A condition of inadequate circulating red blood cells (ANEMIA) or insufficient HEMOGLOBIN due to premature destruction of red blood cells (ERYTHROCYTES). | Acquired anemia due to destruction of red blood cells by physical trauma such as FIBRIN strands in the blood vessels, artificial heart valve, AORTIC COARCTATION. I can also be associated with hematologic diseases such as DISSEMINATED INTRAVASCULAR COAGULATION; HEMOLYTIC-UREMIC SYNDROME; and THROMBOTIC THROMBOCYTOPENIC PURPURA. [MeSH]
MedDRA Code 10027527
MeSH ID D000743
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Anaemia haemolytic, angiopathic | Microangiopathic haemolytic anaemia | Anemia hemolytic, angiopathic | Microangiopathic hemolytic anemia | Anemia, Hemolytic | Hemolytic Anemia | Microangiopathic Hemolytic Anemia | Anemia, Hemolytic, Acquired | Hemolytic Anemia, Acquired | Acquired Hemolytic Anemia | Anemia, Acquired Hemolytic | Anemia, Microangiopathic | Microangiopathic Anemia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00364Carboplatin0.000112%
BADD_D00367Carfilzomib0.000280%
BADD_D00474Cisplatin0.000112%
BADD_D00504Clopidogrel0.000043%
BADD_D00551Cyclosporine--
BADD_D00653Diclofenac0.000026%
BADD_D00800Erlotinib--
BADD_D00858Everolimus0.000336%
BADD_D01009Gemcitabine0.000224%
BADD_D01010Gemcitabine hydrochloride--
BADD_D01281Levonorgestrel0.000473%
BADD_D01478Mitomycin--
BADD_D01506Muromonab-cd3--
BADD_D01633Oxaliplatin0.000112%
BADD_D01643Oxybutynin--
BADD_D01834Prednisone0.000027%
BADD_D01858Propagermanium--
BADD_D01895Quinine0.006605%
BADD_D02100Sunitinib0.000280%
BADD_D02105Tacrolimus0.000743%
BADD_D02324Valacyclovir hydrochloride--
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