Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Hypertonic bladder
ADR ID BADD_A02159
ADR Hierarchy
20      Renal and urinary disorders
20.03      Bladder and bladder neck disorders (excl calculi)
20.03.03      Myoneurogenic bladder disorders
20.03.03.003      Hypertonic bladder
17      Nervous system disorders
17.10      Spinal cord and nerve root disorders
17.10.01      Spinal cord and nerve root disorders NEC
17.10.01.003      Hypertonic bladder
Description Symptom of overactive detrusor muscle of the URINARY BLADDER that contracts with abnormally high frequency and urgency. Overactive bladder is characterized by the frequent feeling of needing to urinate during the day, during the night, or both. URINARY INCONTINENCE may or may not be present. [MeSH]
MedDRA Code 10020853
MeSH ID D053201
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Bladder instability | Detrusor hyperreflexia | Detrusor instability | Hypertonic bladder | Hypertonicity of bladder | Low bladder compliance | Unstable bladder | Hyperactive bladder | Overactive bladder | Urgency-frequency syndrome | Urinary Bladder, Overactive | Overactive Bladder | Overactive Urinary Bladder | Bladder, Overactive | Overactive Detrusor | Detrusor, Overactive | Overactive Detrusor Function | Detrusor Function, Overactive
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000440%
BADD_D00129Amoxicillin--
BADD_D00284Bortezomib--
BADD_D00312Bupropion--
BADD_D00417Cetirizine0.000029%
BADD_D00680Dimethyl fumarate0.000400%
BADD_D00775Enzalutamide0.000734%
BADD_D00794Ergocalciferol0.000684%
BADD_D00891Fesoterodine0.004217%
BADD_D00898Finasteride0.000310%
BADD_D01133Ifosfamide--
BADD_D01228Ketamine0.000714%
BADD_D01250Lasofoxifene--
BADD_D01253Lenalidomide0.005232%
BADD_D01260Leuprolide acetate0.004876%
BADD_D01336Macitentan0.000120%
BADD_D01376Melphalan--
BADD_D01418Methotrexate--
BADD_D01475Mirabegron0.000823%
BADD_D01643Oxybutynin--
BADD_D01654Palbociclib0.000381%
BADD_D01835Pregabalin0.000228%
BADD_D01951Risperidone0.000121%
BADD_D01966Ropinirole--
BADD_D02047Sodium oxybate0.000858%
BADD_D02105Tacrolimus0.000297%
BADD_D02107Tafamidis0.000538%
BADD_D02236Tofacitinib0.001471%
BADD_D02244Tolterodine0.000498%
BADD_D02329Valproic acid0.000300%
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