Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Hyperammonaemia
ADR ID BADD_A02108
ADR Hierarchy
09      Hepatobiliary disorders
09.01      Hepatic and hepatobiliary disorders
09.01.02      Hepatic enzymes and function abnormalities
09.01.02.002      Hyperammonaemia
14      Metabolism and nutrition disorders
14.10      Protein and amino acid metabolism disorders NEC
14.10.01      Protein metabolism disorders NEC
14.10.01.001      Hyperammonaemia
Description Elevated level of AMMONIA in the blood. It is a sign of defective CATABOLISM of AMINO ACIDS or ammonia to UREA. [MeSH]
MedDRA Code 10020575
MeSH ID D022124
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Hyperammonaemia | Hyperammonemia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01304Lithium cation0.000192%
BADD_D01407Methamphetamine0.000094%
BADD_D01414Methimazole0.000202%
BADD_D01599Olanzapine0.000947%
BADD_D01633Oxaliplatin0.000224%
BADD_D01637Oxcarbazepine0.000170%
BADD_D01687Pazopanib0.000112%
BADD_D01760Phenylbutyric acid0.012937%
BADD_D01765Phenytoin0.000669%
BADD_D01831Prednisolone0.000035%
BADD_D01834Prednisone0.000009%
BADD_D01888Quetiapine0.000082%
BADD_D01898Rabeprazole--
BADD_D01899Rabeprazole sodium--
BADD_D01922Regorafenib0.000168%
BADD_D01933Ribavirin0.005934%
BADD_D01951Risperidone0.000485%
BADD_D02028Sirolimus0.000134%
BADD_D02053Sofosbuvir0.001327%
BADD_D02058Sorafenib0.000336%
BADD_D02069Stiripentol0.000125%
BADD_D02100Sunitinib0.000224%
BADD_D02105Tacrolimus0.001040%
BADD_D02147Telmisartan0.000260%
BADD_D02246Tolvaptan0.000058%
BADD_D02247Topiramate0.000382%
BADD_D02329Valproic acid0.008717%
BADD_D02346Venlafaxine0.000032%
BADD_D02396Zonisamide0.000414%
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