Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Extensor plantar response
ADR ID BADD_A01562
ADR Hierarchy
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.01      Abnormal reflexes
17.02.01.005      Extensor plantar response
Description A reflex found in normal infants consisting of dorsiflexion of the HALLUX and abduction of the other TOES in response to cutaneous stimulation of the plantar surface of the FOOT. In adults, it is used as a diagnostic criterion, and if present is a NEUROLOGIC MANIFESTATION of dysfunction in the CENTRAL NERVOUS SYSTEM. [MeSH]
MedDRA Code 10015727
MeSH ID D001405
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Babinski sign positive | Extensor plantar response | Plantar response extensor | Positive Babinski | Positive Babinski response | Reflex Babinski positive | Reflex plantar extensor | Reflex plantar upgoing | Sign Babinski present | Upgoing plantars | Reflex, Babinski | Reflexes, Babinski | Babinski Reflex | Extensor Plantar Response | Great Toe Paradoxical Extensor Reflex | Babinski Sign | Babinski Sign Positive | Babinski's Reflex | Reflex, Babinski's | Babinski's Sign | Extensor Plantar Reflex | Babinski Reflexes | Paradoxical Extensor Reflex, Great Toe | Babinski Sign Absent | Babinski Sign Negative
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00189Atropine--
BADD_D00209Baclofen0.000104%
BADD_D00356Carbamazepine0.000465%
BADD_D00563Dabigatran0.000489%
BADD_D00717Doxapram hydrochloride--
BADD_D00734Duloxetine0.000027%
BADD_D00970Fosphenytoin--
BADD_D00971Fosphenytoin sodium--
BADD_D00981Gabapentin0.000053%
BADD_D01243Lamotrigine0.000083%
BADD_D01265Levetiracetam0.000119%
BADD_D01401Metformin0.000008%
BADD_D01599Olanzapine0.000316%
BADD_D01765Phenytoin0.000382%
BADD_D01834Prednisone0.000009%
BADD_D01854Promethazine0.000058%
BADD_D01954Rivaroxaban0.000127%
BADD_D02105Tacrolimus0.000297%
BADD_D02329Valproic acid0.000250%
BADD_D02346Venlafaxine0.000032%
BADD_D02464Fingolimod0.002025%
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