Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Encephalopathy
ADR ID BADD_A01462
ADR Hierarchy
17      Nervous system disorders
17.13      Encephalopathies
17.13.02      Encephalopathies NEC
17.13.02.001      Encephalopathy
Description A disorder characterized by a pathologic process involving the brain. [CTCAE] Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM. [MeSH]
MedDRA Code 10014625
MeSH ID D001927
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Encephalopathy | Encephalopathy acute | Encephalopathy chronic | Encephalopathy NOS | Encephalopathy, unspecified | Influenza encephalopathy | Static encephalopathy | Mixed-type encephalopathy | Brain Diseases | Brain Disease | Brain Disorders | Brain Disorder | Intracranial CNS Disorders | Central Nervous System Intracranial Disorders | CNS Disorders, Intracranial | CNS Disorder, Intracranial | Intracranial CNS Disorder | Encephalon Diseases | Encephalon Disease | Intracranial Central Nervous System Disorders | Central Nervous System Disorders, Intracranial | Encephalopathies
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01240Lactulose0.000403%
BADD_D01243Lamotrigine0.001131%
BADD_D01254Lenvatinib0.001119%
BADD_D01258Leucovorin0.002478%
BADD_D01265Levetiracetam0.001844%
BADD_D01275Levofloxacin0.000337%
BADD_D01295Linezolid0.008233%
BADD_D01300Lisinopril0.000034%
BADD_D01303Lithium carbonate0.003587%
BADD_D01304Lithium cation0.001248%
BADD_D01318Lorazepam0.000169%
BADD_D01369Mefloquine--
BADD_D01370Mefloquine hydrochloride--
BADD_D01376Melphalan0.000470%
BADD_D01378Memantine0.000181%
BADD_D01379Memantine hydrochloride--
BADD_D01392Mercaptopurine0.001041%
BADD_D01393Meropenem0.000097%
BADD_D01401Metformin0.000310%
BADD_D01405Methadone0.006099%
BADD_D01407Methamphetamine0.000094%
BADD_D01414Methimazole0.000202%
BADD_D01418Methotrexate--
BADD_D01419Methotrexate sodium--
BADD_D01433Methylprednisolone0.000128%
BADD_D01449Metronidazole0.001549%
BADD_D01455Micafungin--
BADD_D01456Micafungin sodium--
BADD_D01465Miglustat0.004312%
BADD_D01479Mitotane--
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ADReCS-Target
ADR Term Drug Name Target