Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Dry eye
ADR ID BADD_A01343
ADR Hierarchy
06      Eye disorders
06.08      Eye disorders NEC
06.08.02      Lacrimation disorders
06.08.02.001      Dry eye
Description A disorder characterized by dryness of the cornea and conjunctiva. [CTCAE] Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur. [MeSH]
MedDRA Code 10013774
MeSH ID D015352; D007638
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Conjunctival xerosis | Dry eye | Dry eye NOS | Dry eye syndrome | Dry eyes | Dryness of eyes | Dryness under lids | Eye dryness | Eyes dry | Keratoconjunctivitis sicca | Keratoconjunctivitis sicca, not specified as Sjogren's | Dry eyes aggravated | Keratitis sicca | Corneal xerosis | Lacrimal gland insufficiency | Dry Eye Syndromes | Dry Eye Syndrome | Syndrome, Dry Eye | Syndromes, Dry Eye
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02031Sitaxentan--
BADD_D02047Sodium oxybate0.004319%
BADD_D02054Solifenacin succinate--
BADD_D02093Sulfasalazine--
BADD_D02104Tacrine hydrochloride--
BADD_D02105Tacrolimus--
BADD_D02108Tafluprost0.001096%
BADD_D02111Tamoxifen--
BADD_D02150Temozolomide--
BADD_D02154Tenofovir0.010857%
BADD_D02160Terbinafine0.000372%
BADD_D02191Tetryzoline--
BADD_D02192Thalidomide0.001760%
BADD_D02219Timolol--
BADD_D02220Timolol maleate--
BADD_D02232Tobramycin--
BADD_D02236Tofacitinib0.085378%
BADD_D02244Tolterodine0.001153%
BADD_D02245Tolterodine tartrate--
BADD_D02246Tolvaptan0.000157%
BADD_D02247Topiramate--
BADD_D02250Toremifene citrate--
BADD_D02254Tramadol--
BADD_D02257Trametinib0.000302%
BADD_D02258Trametinib dimethyl sulfoxide--
BADD_D02265Travoprost0.003086%
BADD_D02266Trazodone--
BADD_D02283Trifluridine--
BADD_D02305Trospium--
BADD_D02306Trospium chloride--
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