Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Dry eye
ADR ID BADD_A01343
ADR Hierarchy
06      Eye disorders
06.08      Eye disorders NEC
06.08.02      Lacrimation disorders
06.08.02.001      Dry eye
Description A disorder characterized by dryness of the cornea and conjunctiva. [CTCAE] Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur. [MeSH]
MedDRA Code 10013774
MeSH ID D015352; D007638
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Conjunctival xerosis | Dry eye | Dry eye NOS | Dry eye syndrome | Dry eyes | Dryness of eyes | Dryness under lids | Eye dryness | Eyes dry | Keratoconjunctivitis sicca | Keratoconjunctivitis sicca, not specified as Sjogren's | Dry eyes aggravated | Keratitis sicca | Corneal xerosis | Lacrimal gland insufficiency | Dry Eye Syndromes | Dry Eye Syndrome | Syndrome, Dry Eye | Syndromes, Dry Eye
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00502Clonidine--
BADD_D00503Clonidine hydrochloride--
BADD_D00539Cromolyn sodium--
BADD_D00545Cyclobenzaprine0.000016%
BADD_D00551Cyclosporine0.009239%
BADD_D00584Darifenacin--
BADD_D00585Darifenacin hydrobromide--
BADD_D00586Darunavir--
BADD_D00589Dasatinib0.001366%
BADD_D00602Delamanid--
BADD_D00603Delavirdine--
BADD_D00604Delavirdine mesylate--
BADD_D00623Dexamethasone0.000436%
BADD_D00636Dextroamphetamine0.001530%
BADD_D00652Dichlorphenamide0.000392%
BADD_D00661Didanosine--
BADD_D00667Difluprednate0.000716%
BADD_D00693Disopyramide--
BADD_D00694Disopyramide phosphate--
BADD_D00696Divalproex sodium--
BADD_D00706Donepezil--
BADD_D00707Donepezil hydrochloride--
BADD_D00713Dorzolamide hydrochloride--
BADD_D00723Doxorubicin--
BADD_D00724Doxorubicin hydrochloride--
BADD_D00734Duloxetine--
BADD_D00735Duloxetine hydrochloride--
BADD_D00754Elazop--
BADD_D00755Eletriptan--
BADD_D00756Eletriptan hydrobromide--
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