Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Dry eye
ADR ID BADD_A01343
ADR Hierarchy
06      Eye disorders
06.08      Eye disorders NEC
06.08.02      Lacrimation disorders
06.08.02.001      Dry eye
Description A disorder characterized by dryness of the cornea and conjunctiva. [CTCAE] Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur. [MeSH]
MedDRA Code 10013774
MeSH ID D015352; D007638
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Conjunctival xerosis | Dry eye | Dry eye NOS | Dry eye syndrome | Dry eyes | Dryness of eyes | Dryness under lids | Eye dryness | Eyes dry | Keratoconjunctivitis sicca | Keratoconjunctivitis sicca, not specified as Sjogren's | Dry eyes aggravated | Keratitis sicca | Corneal xerosis | Lacrimal gland insufficiency | Dry Eye Syndromes | Dry Eye Syndrome | Syndrome, Dry Eye | Syndromes, Dry Eye
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00263Betaxolol--
BADD_D00269Bexarotene--
BADD_D00274Bimatoprost0.016910%
BADD_D00277Bisoprolol0.001256%
BADD_D00283Boceprevir--
BADD_D00284Bortezomib--
BADD_D00290Botulinum toxin type a--
BADD_D00294Brimonidine0.002775%
BADD_D00295Brimonidine tartrate--
BADD_D00296Brinzolamide0.004209%
BADD_D00310Buprenorphine--
BADD_D00312Bupropion--
BADD_D00313Bupropion hydrobromide--
BADD_D00314Bupropion hydrochloride--
BADD_D00315Buserelin acetate--
BADD_D00347Candesartan cilexetil0.000841%
BADD_D00349Capecitabine0.001757%
BADD_D00354Captopril--
BADD_D00356Carbamazepine0.000558%
BADD_D00369Cariprazine0.000444%
BADD_D00382Cefazolin0.000049%
BADD_D00411Celiprolol--
BADD_D00417Cetirizine0.000111%
BADD_D00424Cevimeline0.012346%
BADD_D00463Cidofovir--
BADD_D00464Cidofovir dihydrate--
BADD_D00471Ciprofloxacin--
BADD_D00472Ciprofloxacin hydrochloride--
BADD_D00475Citalopram--
BADD_D00476Citalopram hydrobromide--
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