Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Diaphragmatic paralysis
ADR ID BADD_A01260
ADR Hierarchy
17      Nervous system disorders
17.01      Movement disorders (incl parkinsonism)
17.01.04      Paralysis and paresis (excl cranial nerve)
17.01.04.014      Diaphragmatic paralysis
22      Respiratory, thoracic and mediastinal disorders
22.09      Thoracic disorders (excl lung and pleura)
22.09.02      Diaphragmatic disorders
22.09.02.002      Diaphragmatic paralysis
Description Complete or severe weakness of the muscles of respiration. This condition may be associated with MOTOR NEURON DISEASES; PERIPHERAL NERVE DISEASES; NEUROMUSCULAR JUNCTION DISEASES; SPINAL CORD DISEASES; injury to the PHRENIC NERVE; and other disorders. [MeSH]
MedDRA Code 10012725
MeSH ID D012133
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Diaphragmatic paralysis | Paralysis of diaphragm | Respiratory Paralysis | Paralysis, Respiratory | Paralysis, Respiratory Muscle | Muscle Paralyses, Respiratory | Muscle Paralysis, Respiratory | Respiratory Muscle Paralysis | Diaphragmatic Paralysis | Paralysis, Diaphragmatic
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00085Alprazolam0.000039%
BADD_D00115Amiodarone0.000269%
BADD_D00255Beractant--
BADD_D00308Bupivacaine0.000447%
BADD_D00931Fluorouracil0.000184%
BADD_D00932Fluoxetine0.000020%
BADD_D00979Furosemide0.000014%
BADD_D01336Macitentan0.000265%
BADD_D01867Propranolol0.000134%
BADD_D02105Tacrolimus0.000297%
BADD_D02416Ropivacaine0.000179%
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