Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Delirium
ADR ID BADD_A01178
ADR Hierarchy
19      Psychiatric disorders
19.13      Deliria (incl confusion)
19.13.02      Deliria
19.13.02.001      Delirium
Description A disorder characterized by the acute and sudden development of confusion, illusions, movement changes, inattentiveness, agitation, and hallucinations. Usually, it is a reversible condition. [CTCAE] A disorder characterized by CONFUSION; inattentiveness; disorientation; ILLUSIONS; HALLUCINATIONS; agitation; and in some instances autonomic nervous system overactivity. It may result from toxic/metabolic conditions or structural brain lesions. (From Adams et al., Principles of Neurology, 6th ed, pp411-2) [MeSH]
MedDRA Code 10012218
MeSH ID D003693
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE)
Synonym
Acute brain syndrome | Acute delirium | Brain syndrome acute | Delirious | Delirium | Delirium due to a general medical condition | Delirium nocternal | Delirium nocturnal | Delirium toxic | Delirium, cause unknown | Disorder brain (acute) | Drug-induced delirium | Sensory deprivation delirium | Subacute delirium | Syndrome brain acute | Sundowning | Hypoactive delirium | Hyperactive delirium | Mixed delirium | Subacute Delirium | Delirium, Subacute | Deliriums, Subacute | Subacute Deliriums | Delirium of Mixed Origin | Mixed Origin Delirium | Mixed Origin Deliriums
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01966Ropinirole--
BADD_D01973Rotigotine0.000917%
BADD_D01994Scopolamine0.000884%
BADD_D02002Selegiline--
BADD_D02010Sertraline0.000270%
BADD_D02011Sertraline hydrochloride--
BADD_D02015Sevoflurane0.000447%
BADD_D02018Sildenafil--
BADD_D02029Sitagliptin0.000133%
BADD_D02047Sodium oxybate0.002843%
BADD_D02054Solifenacin succinate--
BADD_D02103Suvorexant0.001267%
BADD_D02104Tacrine hydrochloride--
BADD_D02105Tacrolimus0.003119%
BADD_D02115Tapentadol0.009237%
BADD_D02147Telmisartan0.000390%
BADD_D02148Temazepam0.000180%
BADD_D02160Terbinafine0.000298%
BADD_D02175Tetrabenazine0.002261%
BADD_D02192Thalidomide--
BADD_D02197Thiamine0.000947%
BADD_D02203Thiotepa--
BADD_D02232Tobramycin--
BADD_D02241Tolcapone--
BADD_D02246Tolvaptan0.000145%
BADD_D02247Topiramate--
BADD_D02254Tramadol0.000116%
BADD_D02270Tretinoin0.000107%
BADD_D02277Triazolam0.003827%
BADD_D02290Trimethoprim0.000525%
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