Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Crohn's disease
ADR ID BADD_A01117
ADR Hierarchy
10      Immune system disorders
10.02      Immune disorders NEC
10.02.01      Immune and associated conditions NEC
10.02.01.005      Crohn's disease
07      Gastrointestinal disorders
07.08      Gastrointestinal inflammatory conditions
07.08.01      Colitis (excl infective)
07.08.01.015      Crohn's disease
Description A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients. [MeSH]
MedDRA Code 10011401
MeSH ID D003424; D003424; D003424
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Crohn's | Crohn's aggravated | Crohn's colitis | Crohn's disease | Crohn's disease (colon) | Crohn's disease aggravated | Crohn's duodenitis | Crohn's enteritis | Crohn's ileitis | Crohns disease aggravated | Disease Crohns | Ileitis regional | Regional enteritis | Regional enteritis of large intestine | Regional enteritis of small intestine | Regional enteritis of small intestine with large intestine | Regional enteritis of unspecified site | Regional ileitis aggravated | Granulomatous colitis | Crohn's ileocolitis | Granulomatous ileocolitis | Granulomatous ileitis | Crohn's disease acute episode | Fistulizing Crohn's disease | Fistulising Crohn's disease | Crohn's disease relapse | Fibrostenotic Crohn's disease | Crohn Disease | Crohn's Enteritis | Regional Enteritis | Crohn's Disease | Crohns Disease | Inflammatory Bowel Disease 1 | Enteritis, Granulomatous | Granulomatous Enteritis | Enteritis, Regional | Ileocolitis | Colitis, Granulomatous | Granulomatous Colitis | Ileitis, Terminal | Terminal Ileitis | Ileitis, Regional | Regional Ileitides | Regional Ileitis
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01087Hydrocortisone acetate--
BADD_D01096Hydromorphone--
BADD_D01120Ibuprofen--
BADD_D01156Indomethacin--
BADD_D01157Infliximab--
BADD_D01171Interferon gamma-1b--
BADD_D01197Iron0.003355%
BADD_D01213Isotretinoin0.206066%
BADD_D01231Ketoprofen--
BADD_D01232Ketorolac--
BADD_D01233Ketorolac tromethamine--
BADD_D01245Lansoprazole0.000348%
BADD_D01285Levothyroxine0.000038%
BADD_D01392Mercaptopurine0.011658%
BADD_D01393Meropenem0.000073%
BADD_D01397Mesalamine0.008160%
BADD_D01401Metformin--
BADD_D01414Methimazole--
BADD_D01418Methotrexate0.003059%
BADD_D01433Methylprednisolone--
BADD_D01449Metronidazole0.000320%
BADD_D01465Miglustat0.006469%
BADD_D01476Mirtazapine--
BADD_D01533Naproxen--
BADD_D01534Naproxen sodium--
BADD_D01585Norethindrone--
BADD_D01592Obeticholic acid0.002085%
BADD_D01602Olmesartan0.000839%
BADD_D01614Omeprazole0.000013%
BADD_D01617Ondansetron0.000021%
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