| Pharmaceutical Information |
| Drug Name |
Ketorolac |
| Drug ID |
BADD_D01232 |
| Description |
Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution.[L6358][L6508][L11055][L3674][L11070]
It's analgesic properties make it a useful pain management tool across many settings including postoperative pain, rheumatoid arthritis, osteoarthritis, menstrual disorders, headaches, spinal and soft tissue pain, and ankylosing spondylitis.[L6520] Impressively, ketorolac has a similar efficacy to standard doses of morphine and meperidine making it a useful opioid sparing agent.[L6511] |
| Indications and Usage |
Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and has antipyretic, analgesic and anti-inflammatory properties.[A176131] It is indicated for short term management of acute pain that requires the calibre of pain management offered by opioids.[L3674] Clinicians may choose to initiate ketorolac to manage post-operative pain, spinal and soft tissue pain, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, menstrual disorders and headaches among other ailments.[L6520] Regardless of the etiology of pain, patients should use the lowest possible dose, and avoid using ketorolac for an extended period of time (ideally ≤ 5 days).[L3674] A benefit of choosing ketorolac over other analgesics with similar potency is that that there does not appear to be a risk of dependence or tolerance with ketorolac use.[A176131] |
| Marketing Status |
approved |
| ATC Code |
M01AB15; S01BC05 |
| DrugBank ID |
DB00465
|
| KEGG ID |
D08104
|
| MeSH ID |
D020910
|
| PubChem ID |
3826
|
| TTD Drug ID |
D0D9JW
|
| NDC Product Code |
Not Available |
| UNII |
YZI5105V0L
|
| Synonyms |
Ketorolac |
|
| Chemical Information |
| Molecular Formula |
C15H13NO3 |
| CAS Registry Number |
74103-06-3 |
| SMILES |
C1CN2C(=CC=C2C(=O)C3=CC=CC=C3)C1C(=O)O |
| Chemical Structure |
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| ADRs Induced by Drug |
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