Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Constipation
ADR ID BADD_A01059
ADR Hierarchy
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.02      Gastrointestinal atonic and hypomotility disorders NEC
07.02.02.001      Constipation
Description A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. [CTCAE] Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections. | Difficult defecation. | Symptom characterized by the passage of stool once a week or less. [MeSH]
MedDRA Code 10010774
MeSH ID D003248
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Constipation | Constipation (excl faecal impaction) | Iatrogenic constipation | Obstipation | Constipation aggravated | Constipation (excl fecal impaction) | Stools absent | Constipation chronic | Opioid induced constipation | Slow transit constipation | Chronic idiopathic constipation | Absent bowel movement | Habitual constipation | Dyschezia | Colonic Inertia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00291Brentuximab vedotin--
BADD_D00293Brexpiprazole--
BADD_D00304Bromocriptine--
BADD_D00305Bromocriptine mesylate--
BADD_D00306Budesonide--
BADD_D00308Bupivacaine--
BADD_D00310Buprenorphine0.030994%
BADD_D00311Buprenorphine hydrochloride--
BADD_D00312Bupropion--
BADD_D00313Bupropion hydrobromide--
BADD_D00314Bupropion hydrochloride--
BADD_D00315Buserelin acetate--
BADD_D00316Buspirone--
BADD_D00318Busulfan--
BADD_D00319Butabarbital--
BADD_D00320Butabarbital sodium--
BADD_D00324Butorphanol--
BADD_D00325Butorphanol tartrate--
BADD_D00328Cabazitaxel--
BADD_D00329Cabergoline0.039877%
BADD_D00330Cabozantinib0.011820%
BADD_D00331Cabozantinib s-malate--
BADD_D00332Caffeine--
BADD_D00335Calcitonin--
BADD_D00336Calcitonin (salmon)--
BADD_D00337Calcitriol--
BADD_D00338Calcium acetate--
BADD_D00341Calcium ion--
BADD_D00343Californium-249 oxide--
BADD_D00344Canagliflozin--
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