Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Butorphanol tartrate
Drug ID BADD_D00325
Description A synthetic morphinan analgesic with narcotic antagonist action. It is used in the management of severe pain.
Indications and Usage For the relief of moderate to severe pain.
Marketing Status approved; illicit; vet_approved
ATC Code N02AF01
DrugBank ID DB00611
KEGG ID D00837
MeSH ID D002077
PubChem ID 5462346
TTD Drug ID D0X9RG
NDC Product Code 0409-1623; 62991-3162; 0143-9864; 0054-3090; 60505-0813; 0409-1626; 47848-005; 0143-9867; 38779-1765; 66651-920
UNII 2L7I72RUHN
Synonyms Butorphanol | 17-(Cyclobutylmethyl)morphinan-3,14-diol | BC-2627 | BC 2627 | BC2627 | Beforal | Butorphanol Tartrate | Moradol | Stadol | Stadol NS | Torbugesic | Apo-Butorphanol | Dolorex
Chemical Information
Molecular Formula C25H35NO8
CAS Registry Number 58786-99-5
SMILES C1CCC2(C3CC4=C(C2(C1)CCN3CC5CCC5)C=C(C=C4)O)O.C(C(C(=O)O)O)(C(=O)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain upper07.01.05.003--
Abnormal dreams17.15.02.001; 19.02.03.001---
Agitation17.02.05.012; 19.06.02.001--
Anxiety19.06.02.002--
Apnoea22.02.01.001--
Asthenia08.01.01.001---
Bronchitis11.01.09.001; 22.07.01.001--
Chest pain02.02.02.011; 08.01.08.002; 22.12.02.003---
Cold sweat08.01.03.024; 23.02.03.002---
Confusional state17.02.03.005; 19.13.01.001--
Constipation07.02.02.001--
Cough22.02.03.001--
Delusion19.10.01.001--
Depression19.15.01.001--
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Drug dependence19.07.06.011---
Dry mouth07.06.01.002--
Dysgeusia07.14.03.001; 17.02.07.003--
Dysphoria19.04.02.004---
Dyspnoea02.11.05.003; 22.02.01.004--
Dysuria20.02.02.002--
Ear pain04.03.01.003--
Epistaxis22.04.03.001; 24.07.01.005--
Euphoric mood19.04.02.006--
Feeling abnormal08.01.09.014---
Feeling hot08.01.09.009---
Hallucination19.10.04.003--
Headache17.14.01.001--
Hostility19.05.01.003---
Hyperhidrosis08.01.03.028; 23.02.03.004--
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