Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Butorphanol tartrate
Drug ID BADD_D00325
Description A synthetic morphinan analgesic with narcotic antagonist action. It is used in the management of severe pain.
Indications and Usage For the relief of moderate to severe pain.
Marketing Status Prescription; Discontinued
ATC Code N02AF01
DrugBank ID DB00611
KEGG ID D00837
MeSH ID D002077
PubChem ID 5462346
TTD Drug ID D0X9RG
NDC Product Code 38779-1765; 0143-9867; 0409-1626; 0143-9864; 47848-005; 60505-0813; 0409-1623; 0054-3090; 62991-3162; 51927-2986; 66651-920
Synonyms Butorphanol | 17-(Cyclobutylmethyl)morphinan-3,14-diol | BC-2627 | BC 2627 | BC2627 | Beforal | Butorphanol Tartrate | Moradol | Stadol | Stadol NS | Torbugesic | Apo-Butorphanol | Dolorex
Chemical Information
Molecular Formula C25H35NO8
CAS Registry Number 58786-99-5
SMILES C1CCC2(C3CC4=C(C2(C1)CCN3CC5CCC5)C=C(C=C4)O)O.C(C(C(=O)O)O)(C(=O)O)O
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain upper07.01.05.003--
Abnormal dreams17.15.02.001; 19.02.03.001--Not Available
Agitation17.02.05.012; 19.06.02.001--
Anxiety19.06.02.002--
Apnoea22.02.01.001--
Asthenia08.01.01.001--Not Available
Bronchitis11.01.09.001; 22.07.01.001--
Chest pain02.02.02.011; 08.01.08.002; 22.02.08.003--Not Available
Cold sweat08.01.03.024; 23.02.03.002--Not Available
Confusional state17.02.03.005; 19.13.01.001--
Constipation07.02.02.001--
Cough22.02.03.001--
Delusion19.10.01.001--
Depression19.15.01.001--
Dizziness02.01.02.004; 17.02.05.003; 24.06.02.007--
Drug dependence19.07.02.009--Not Available
Dry mouth07.06.01.002--
Dysgeusia07.14.03.001; 17.02.07.003--
Dysphoria19.04.02.004--Not Available
Dyspnoea02.01.03.002; 22.02.01.004--
Dysuria20.02.02.002--
Ear pain04.03.01.003--
Epistaxis22.04.03.001; 24.07.01.005--
Euphoric mood19.04.02.006--
Feeling abnormal08.01.09.014--Not Available
Feeling hot08.01.09.009--Not Available
Hallucination19.10.02.002--
Headache17.14.01.001--
Hostility19.05.01.003--Not Available
Hyperhidrosis08.01.03.028; 23.02.03.004--
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