Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Constipation
ADR ID BADD_A01059
ADR Hierarchy
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.02      Gastrointestinal atonic and hypomotility disorders NEC
07.02.02.001      Constipation
Description A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. [CTCAE] Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections. | Difficult defecation. | Symptom characterized by the passage of stool once a week or less. [MeSH]
MedDRA Code 10010774
MeSH ID D003248
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Constipation | Constipation (excl faecal impaction) | Iatrogenic constipation | Obstipation | Constipation aggravated | Constipation (excl fecal impaction) | Stools absent | Constipation chronic | Opioid induced constipation | Slow transit constipation | Chronic idiopathic constipation | Absent bowel movement | Habitual constipation | Dyschezia | Colonic Inertia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00877Fenoprofen--
BADD_D00878Fenoprofen calcium--
BADD_D00879Fentanyl--
BADD_D00880Fentanyl citrate--
BADD_D00881Fentanyl hydrochloride--
BADD_D00882Ferric carboxymaltose--
BADD_D00883Ferric oxyhydroxide-
BADD_D00884Ferric pyrophosphate--
BADD_D00885Ferrocyanide ion--
BADD_D00886Ferrosoferric oxide--
BADD_D00890Ferumoxytol non-stoichiometric magnetite--
BADD_D00891Fesoterodine0.020838%
BADD_D00892Fesoterodine fumarate--
BADD_D00896Fidaxomicin0.000444%
BADD_D00897Filgrastim--
BADD_D00898Finasteride0.000939%
BADD_D00902Flecainide--
BADD_D00903Flecainide acetate--
BADD_D00904Flibanserin--
BADD_D00911Flucloxacillin--
BADD_D00912Fluconazole--
BADD_D00914Fludarabine--
BADD_D00915Fludarabine phosphate--
BADD_D00920Flunisolide--
BADD_D00921Flunisolide hemihydrate--
BADD_D00932Fluoxetine--
BADD_D00933Fluoxetine hydrochloride--
BADD_D00935Fluphenazine--
BADD_D00936Fluphenazine decanoate--
BADD_D00937Fluphenazine hydrochloride--
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