Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Compartment syndrome
ADR ID BADD_A00989
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.05      Muscle disorders
15.05.05      Myopathies
15.05.05.005      Compartment syndrome
24      Vascular disorders
24.04      Arteriosclerosis, stenosis, vascular insufficiency and necrosis
24.04.05      Musculoskeletal necrosis and vascular insufficiency
24.04.05.006      Compartment syndrome
Description Conditions in which increased pressure within a limited space compromises the BLOOD CIRCULATION and function of tissue within that space. Some of the causes of increased pressure are TRAUMA, tight dressings, HEMORRHAGE, and exercise. Sequelae include nerve compression (NERVE COMPRESSION SYNDROMES); PARALYSIS; and ISCHEMIC CONTRACTURE. [MeSH]
MedDRA Code 10010121
MeSH ID D003161
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Compartment syndrome | Chronic exertional compartment syndrome | Acute compartment syndrome | Compartment Syndromes | Compartment Syndrome | Syndrome, Compartment | Syndromes, Compartment
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01376Melphalan0.000112%
BADD_D01401Metformin0.000014%
BADD_D01405Methadone0.001193%
BADD_D01431Methylphenidate0.000041%
BADD_D01498Morphine0.001002%
BADD_D01567Nilotinib0.000112%
BADD_D01579Nitroglycerin--
BADD_D01583Norepinephrine0.000127%
BADD_D01599Olanzapine0.000842%
BADD_D01653Paclitaxel0.000224%
BADD_D01710Penicillin g0.007985%
BADD_D01762Phenylephrine0.002066%
BADD_D01765Phenytoin0.000860%
BADD_D01835Pregabalin0.000156%
BADD_D01864Propofol0.000268%
BADD_D01888Quetiapine0.000082%
BADD_D01909Ramipril0.000373%
BADD_D01951Risperidone0.000303%
BADD_D01954Rivaroxaban0.001267%
BADD_D02026Simvastatin0.000036%
BADD_D02214Ticagrelor0.000544%
BADD_D02346Venlafaxine0.000048%
BADD_D02373Warfarin0.000575%
BADD_D02375Water--
BADD_D02394Zolpidem0.000025%
BADD_D02423Fondaparinux0.009868%
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