Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Cachexia
ADR ID BADD_A00741
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.009      Cachexia
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.32      Neoplasm related morbidities
16.32.03      Oncologic complications and emergencies
16.32.03.011      Cachexia
14      Metabolism and nutrition disorders
14.03      Appetite and general nutritional disorders
14.03.02      General nutritional disorders NEC
14.03.02.001      Cachexia
Description General ill health, malnutrition, and weight loss, usually associated with chronic disease. [MeSH]
MedDRA Code 10006895
MeSH ID D002100; D004614
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Cachexia | Emaciation | Wasting | Wasting generalized | Cardiac cachexia | Cancer cachexia | Constitutional syndrome | Wasting generalised | Cachexia-anorexia syndrome
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02100Sunitinib0.000560%
BADD_D02104Tacrine hydrochloride--
BADD_D02105Tacrolimus0.000594%
BADD_D02248Topotecan--
BADD_D02257Trametinib0.000168%
BADD_D02326Valganciclovir--
BADD_D02365Vismodegib0.000302%
BADD_D02375Water--
BADD_D02378Zalcitabine--
BADD_D02412Octreotide--
BADD_D02434Cinacalcet0.000586%
BADD_D02470Nintedanib0.000168%
BADD_D02504Lorlatinib0.000112%
BADD_D02586Radium ra-223 dichloride-
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