Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Blood creatine phosphokinase
ADR ID BADD_A00533
ADR Hierarchy
13      Investigations
13.04      Enzyme investigations NEC
13.04.01      Skeletal and cardiac muscle analyses
13.04.01.009      Blood creatine phosphokinase
Description A transferase that catalyzes formation of PHOSPHOCREATINE from ATP + CREATINE. The reaction stores ATP energy as phosphocreatine. Three cytoplasmic ISOENZYMES have been identified in human tissues: the MM type from SKELETAL MUSCLE, the MB type from myocardial tissue and the BB type from nervous tissue as well as a mitochondrial isoenzyme. Macro-creatine kinase refers to creatine kinase complexed with other serum proteins. [MeSH]
MedDRA Code 10005467
MeSH ID D003402
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Blood creatine phosphokinase | CK | CPK | Creatine kinase | Creatine phosphokinase | Plasma creatine phosphokinase | Serum creatine phosphokinase | Creatine Kinase | Kinase, Creatine | ATP Creatine Phosphotransferase | Creatine Phosphotransferase, ATP | Phosphotransferase, ATP Creatine | Creatine Phosphokinase | Phosphokinase, Creatine | ADP Phosphocreatine Phosphotransferase | Phosphocreatine Phosphotransferase, ADP | Phosphotransferase, ADP Phosphocreatine | Macro-Creatine Kinase | Macro Creatine Kinase
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00503Clonidine hydrochloride--
BADD_D00512Cobicistat--
BADD_D00704Dolutegravir sodium--
BADD_D00707Donepezil hydrochloride--
BADD_D00735Duloxetine hydrochloride--
BADD_D00756Eletriptan hydrobromide--
BADD_D00762Elvitegravir--
BADD_D00766Emtricitabine--
BADD_D00771Enfuvirtide--
BADD_D01352Maraviroc--
BADD_D01550Nelfinavir mesylate--
BADD_D01732Peramivir--
BADD_D02101Sunitinib malate--
BADD_D02156Tenofovir disoproxil fumarate--
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