Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Bipolar I disorder
ADR ID BADD_A00461
ADR Hierarchy
19      Psychiatric disorders
19.16      Manic and bipolar mood disorders and disturbances
19.16.01      Bipolar disorders
19.16.01.002      Bipolar I disorder
Description A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence. [MeSH]
MedDRA Code 10004939
MeSH ID D001714
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Bipolar affective disorder, depressed | Bipolar affective disorder, depressed, in full remission | Bipolar affective disorder, depressed, in partial or unspecified remission | Bipolar affective disorder, depressed, mild degree | Bipolar affective disorder, depressed, moderate degree | Bipolar affective disorder, depressed, severe degree, specified as with psychotic behavior | Bipolar affective disorder, depressed, severe degree, without mention of psychotic behavior | Bipolar affective disorder, depressed, unspecified degree | Bipolar affective disorder, manic | Bipolar affective disorder, manic, in full remission | Bipolar affective disorder, manic, in partial or unspecified remission | Bipolar affective disorder, manic, mild degree | Bipolar affective disorder, manic, moderate degree | Bipolar affective disorder, manic, severe degree, specified as with psychotic behavior | Bipolar affective disorder, manic, severe degree, without mention of psychotic behavior | Bipolar affective disorder, manic, unspecified degree | Bipolar affective disorder, mixed | Bipolar affective disorder, mixed, in full remission | Bipolar affective disorder, mixed, in partial or unspecified remission | Bipolar affective disorder, mixed, mild degree | Bipolar affective disorder, mixed, moderate degree | Bipolar affective disorder, mixed, severe degree, specified as with psychotic behavior | Bipolar affective disorder, mixed, severe degree, without mention of psychotic behavior | Bipolar affective disorder, mixed, unspecified degree | Bipolar I disorder | Cycloid psychoses | Manic depression | Manic depressive | Manic depressive illness | Manic depressive psychosis | Manic depressive reaction | Manic-depressive psychosis, circular type but currently depressed | Manic-depressive psychosis, circular type but currently manic | Manic-depressive psychosis, circular type, current condition not specified | Manic-depressive psychosis, circular type, mixed | Manic-depressive psychosis, other and unspecified | Manic-depressive psychosis, unspecified | Manic-depressive psychosis, depressed type | Manic-depressive psychosis, manic type | Mixed affective disorder (psychosis) | Other and unspecified manic-depressive psychosis | Other manic-depressive psychosis | Psychosis manic-depressive | Reaction manic-depressive | Mixed manic depressive episode | Bipolar I disorder, hypomanic | Bipolar Disorder | Bipolar Disorders | Disorder, Bipolar | Psychosis, Manic-Depressive | Psychosis, Manic Depressive | Manic-Depressive Psychosis | Manic Depressive Psychosis | Affective Psychosis, Bipolar | Bipolar Affective Psychosis | Psychoses, Bipolar Affective | Psychosis, Bipolar Affective | Psychoses, Manic-Depressive | Manic-Depressive Psychoses | Psychoses, Manic Depressive | Mania | Manias | Manic State | Manic States | State, Manic | States, Manic | Depression, Bipolar | Bipolar Depression | Manic Disorder | Disorder, Manic | Manic Disorders
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00156Apremilast0.000892%
BADD_D00165Aripiprazole0.000159%
BADD_D00173Asenapine maleate--
BADD_D00209Baclofen0.000104%
BADD_D00283Boceprevir--
BADD_D00312Bupropion0.000055%
BADD_D00356Carbamazepine0.000372%
BADD_D00511Clozapine0.002446%
BADD_D00734Duloxetine0.000072%
BADD_D00809Escitalopram0.000028%
BADD_D00898Finasteride0.000189%
BADD_D00932Fluoxetine0.000049%
BADD_D01167Interferon alfa-2b--
BADD_D01213Isotretinoin0.001801%
BADD_D01243Lamotrigine0.000055%
BADD_D01281Levonorgestrel0.000473%
BADD_D01318Lorazepam0.000120%
BADD_D01330Lurasidone0.000885%
BADD_D01431Methylphenidate0.000041%
BADD_D01599Olanzapine0.000421%
BADD_D01656Paliperidone0.002049%
BADD_D01679Paroxetine--
BADD_D01680Paroxetine hydrochloride--
BADD_D01681Paroxetine hydrochloride hemihydrate--
BADD_D01682Paroxetine impurity a--
BADD_D01683Paroxetine mesylate--
BADD_D01835Pregabalin0.000130%
BADD_D01888Quetiapine0.000213%
BADD_D01916Rasagiline mesylate--
BADD_D01933Ribavirin0.005934%
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