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ADR Term
ADReCS ID
MedDRA Code
MeSH ID
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ADR Ontology
ADR Term
Apathy
ADR ID
BADD_A00290
ADR Hierarchy
19
Psychiatric disorders
19.04
Mood disorders and disturbances NEC
19.04.04
Mood disorders NEC
19.04.04.002
Apathy
Description
Lack of emotion or emotional expression; a disorder of motivation that persists over time. [MeSH]
MedDRA Code
10002942
MeSH ID
D057565
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Not Available
Synonym
Ambition loss of | Apathy | Initiative loss of | Lack of motivation | Loss of ambition | Loss of initiative | Avolition | Apragmatism | Athymhormia | Lack of volition
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D02099
Sumatriptan succinate
-
-
BADD_D02104
Tacrine hydrochloride
-
-
BADD_D02118
Tasimelteon
0.000444%
BADD_D02150
Temozolomide
-
-
BADD_D02210
Tiagabine
-
-
BADD_D02211
Tiagabine hydrochloride
-
-
BADD_D02241
Tolcapone
-
-
BADD_D02247
Topiramate
0.000261%
BADD_D02254
Tramadol
0.000014%
BADD_D02259
Trandolapril
-
-
BADD_D02281
Trifluoperazine
-
-
BADD_D02329
Valproic acid
0.000300%
BADD_D02337
Varenicline
0.002472%
BADD_D02346
Venlafaxine
0.000071%
BADD_D02347
Venlafaxine hydrochloride
-
-
BADD_D02355
Vigabatrin
-
-
BADD_D02371
Vortioxetine
-
-
BADD_D02379
Zaleplon
-
-
BADD_D02393
Zolmitriptan
-
-
BADD_D02394
Zolpidem
0.000064%
BADD_D02395
Zolpidem tartrate
-
-
BADD_D02398
Zuclopenthixol
-
-
BADD_D02436
Atorvastatin
-
-
BADD_D02439
Levodopa
0.000550%
BADD_D02440
Lisdexamfetamine
0.000424%
BADD_D02445
Solifenacin
0.000174%
BADD_D02464
Fingolimod
0.002025%
BADD_D02468
Cannabidiol
0.000423%
BADD_D02470
Nintedanib
-
-
BADD_D02491
Valbenazine
0.005760%
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