Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Tiagabine hydrochloride
Drug ID BADD_D02211
Description Tiagabine is an anti-convulsive medication. It is also used in the treatment for panic disorder as are a few other anticonvulsants. Though the exact mechanism by which tiagabine exerts its effect on the human body is unknown, it does appear to operate as a selective GABA reuptake inhibitor.
Indications and Usage For the treatment of partial seizures
Marketing Status approved; investigational
ATC Code N03AG06
DrugBank ID DB00906
KEGG ID D02097
MeSH ID D000078308
PubChem ID 91274
TTD Drug ID D0ED7U
NDC Product Code 63459-416; 63459-412; 82019-0004; 16714-151; 0093-5031; 0093-8072; 63459-404; 72205-086; 16714-153; 29902-0004; 62756-224; 72205-085; 16714-152; 16714-154; 63459-402; 69766-061; 0093-8076; 72205-084; 0093-5030; 62756-200; 72205-087
UNII DQH6T6D8OY
Synonyms Tiagabine | N-(4,4-di(3-Methylthien-2-yl)but-3-enyl)nipecotic acid | Gabitril | NO 329 | NO-329 | Tiagabine Hydrochloride | (R)-(4,4-bis(3-Methyl-2-thienyl)-3-butenyl)-3-piperidinecarboxylic acid, Hydrochloride | Tiagabine, (S)-isomer | NO 328 | NO-328
Chemical Information
Molecular Formula C20H26ClNO2S2
CAS Registry Number 145821-59-6
SMILES CC1=C(SC=C1)C(=CCCN2CCCC(C2)C(=O)O)C3=C(C=CS3)C.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Abnormal dreams17.15.02.001; 19.02.03.001---
Abnormal faeces07.01.03.001---
Abortion18.01.01.001---
Abscess11.01.08.001---
Ageusia07.14.03.003; 17.02.07.001---
Agitation17.02.05.012; 19.06.02.001--
Alopecia23.02.02.001--
Amblyopia06.02.01.001---
Amenorrhoea05.05.01.002; 21.01.02.001--
Anaemia01.03.02.001--
Angina pectoris02.02.02.002; 24.04.04.002--
Apathy19.04.04.002---
Apnoea22.02.01.001--
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Asthenia08.01.01.001---
Asthma10.01.03.010; 22.03.01.002---
Ataxia08.01.02.004; 17.02.02.001--
Benign neoplasm of skin16.26.01.006; 23.10.01.006---
Blepharitis06.04.04.001; 23.03.04.012---
Blindness06.02.10.003; 17.17.01.003---
Breast enlargement21.05.04.001---
Breast pain21.05.05.003--
Breath odour07.01.06.002---
Bronchitis11.01.09.001; 22.07.01.001--
Bursitis12.04.03.010; 15.04.01.001---
Cellulitis11.02.01.001; 23.11.02.004---
Central nervous system neoplasm16.30.01.001; 17.20.01.001---
Cerebral ischaemia17.08.01.005; 24.04.06.003--
The 1th Page    1 2 3 4 5    Next   Last    Total 8 Pages