Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Anterior spinal artery syndrome
ADR ID BADD_A00262
ADR Hierarchy
17      Nervous system disorders
17.10      Spinal cord and nerve root disorders
17.10.01      Spinal cord and nerve root disorders NEC
17.10.01.008      Anterior spinal artery syndrome
24      Vascular disorders
24.04      Arteriosclerosis, stenosis, vascular insufficiency and necrosis
24.04.06      Cerebrovascular and spinal necrosis and vascular insufficiency
24.04.06.015      Anterior spinal artery syndrome
Description Ischemia or infarction of the spinal cord in the distribution of the anterior spinal artery, which supplies the ventral two-thirds of the spinal cord. This condition is usually associated with ATHEROSCLEROSIS of the aorta and may result from dissection of an AORTIC ANEURYSM or rarely dissection of the anterior spinal artery. Clinical features include weakness and loss of pain and temperature sensation below the level of injury, with relative sparing of position and vibratory sensation. (From Adams et al., Principles of Neurology, 6th ed, pp1249-50) [MeSH]
MedDRA Code 10002703
MeSH ID D020759
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Anterior spinal artery syndrome | Anterior Spinal Artery Syndrome | Syndrome, Anterior Spinal Artery | Anterior Spinal Artery Dissection | Dissection, Anterior Spinal Artery
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00308Bupivacaine--
BADD_D00349Capecitabine0.000168%
BADD_D01287Lidocaine--
BADD_D01498Morphine0.000223%
BADD_D01831Prednisolone0.000035%
BADD_D01968Ropivacaine hydrochloride--
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