Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Anal fistula
ADR ID BADD_A00207
ADR Hierarchy
07      Gastrointestinal disorders
07.11      Gastrointestinal conditions NEC
07.11.05      Gastrointestinal fistulae
07.11.05.002      Anal fistula
Description A disorder characterized by an abnormal communication between the opening in the anal canal to the perianal skin. [CTCAE] An abnormal anatomical passage connecting the RECTUM to the outside, with an orifice at the site of drainage. [MeSH]
MedDRA Code 10002156
MeSH ID D012003
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Anal fissure and fistula | Anal fistula | Anorectal fistula | Fistula anal | Fistula in ano | Rectal fistula | Rectum to skin fistula | Perianal fistula | Trans-sphincteric fistula | Rectal Fistula | Fistula, Rectal | Anal Fistula
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000044%
BADD_D00193Axitinib0.000112%
BADD_D00194Azacitidine0.000168%
BADD_D00195Azathioprine0.005546%
BADD_D00306Budesonide0.000233%
BADD_D00330Cabozantinib0.000694%
BADD_D00471Ciprofloxacin--
BADD_D00560Cytarabine0.000168%
BADD_D00589Dasatinib--
BADD_D00794Ergocalciferol0.000684%
BADD_D00898Finasteride0.000045%
BADD_D00952Folic acid--
BADD_D01197Iron--
BADD_D01213Isotretinoin0.023156%
BADD_D01260Leuprolide acetate--
BADD_D01285Levothyroxine0.000007%
BADD_D01392Mercaptopurine0.001041%
BADD_D01397Mesalamine0.000183%
BADD_D01418Methotrexate0.000227%
BADD_D01449Metronidazole0.000026%
BADD_D01668Pantoprazole0.000016%
BADD_D01783Pirfenidone0.000241%
BADD_D01831Prednisolone0.000070%
BADD_D01834Prednisone0.000022%
BADD_D01922Regorafenib0.000280%
BADD_D01933Ribavirin0.005934%
BADD_D02093Sulfasalazine0.000303%
BADD_D02100Sunitinib0.000694%
BADD_D02165Teriflunomide0.000530%
BADD_D02236Tofacitinib--
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