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ADR Ontology
ADR Term
Anal fistula
ADR ID
BADD_A00207
ADR Hierarchy
07
Gastrointestinal disorders
07.11
Gastrointestinal conditions NEC
07.11.05
Gastrointestinal fistulae
07.11.05.002
Anal fistula
Description
A disorder characterized by an abnormal communication between the opening in the anal canal to the perianal skin. [CTCAE] An abnormal anatomical passage connecting the RECTUM to the outside, with an orifice at the site of drainage. [MeSH]
MedDRA Code
10002156
MeSH ID
D012003
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Anal fissure and fistula | Anal fistula | Anorectal fistula | Fistula anal | Fistula in ano | Rectal fistula | Rectum to skin fistula | Perianal fistula | Trans-sphincteric fistula | Rectal Fistula | Fistula, Rectal | Anal Fistula
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D00066
Alendronic acid
0.000044%
BADD_D00193
Axitinib
0.000112%
BADD_D00194
Azacitidine
0.000168%
BADD_D00195
Azathioprine
0.005546%
BADD_D00306
Budesonide
0.000233%
BADD_D00330
Cabozantinib
0.000694%
BADD_D00471
Ciprofloxacin
-
-
BADD_D00560
Cytarabine
0.000168%
BADD_D00589
Dasatinib
-
-
BADD_D00794
Ergocalciferol
0.000684%
BADD_D00898
Finasteride
0.000045%
BADD_D00952
Folic acid
-
-
BADD_D01197
Iron
-
-
BADD_D01213
Isotretinoin
0.023156%
BADD_D01260
Leuprolide acetate
-
-
BADD_D01285
Levothyroxine
0.000007%
BADD_D01392
Mercaptopurine
0.001041%
BADD_D01397
Mesalamine
0.000183%
BADD_D01418
Methotrexate
0.000227%
BADD_D01449
Metronidazole
0.000026%
BADD_D01668
Pantoprazole
0.000016%
BADD_D01783
Pirfenidone
0.000241%
BADD_D01831
Prednisolone
0.000070%
BADD_D01834
Prednisone
0.000022%
BADD_D01922
Regorafenib
0.000280%
BADD_D01933
Ribavirin
0.005934%
BADD_D02093
Sulfasalazine
0.000303%
BADD_D02100
Sunitinib
0.000694%
BADD_D02165
Teriflunomide
0.000530%
BADD_D02236
Tofacitinib
-
-
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