Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Anal fissure
ADR ID BADD_A00206
ADR Hierarchy
07      Gastrointestinal disorders
07.03      Anal and rectal conditions NEC
07.03.01      Anal and rectal disorders NEC
07.03.01.002      Anal fissure
Description A disorder characterized by a tear in the lining of the anus. [CTCAE] A painful linear ulcer at the margin of the anus. It appears as a crack or slit in the mucous membrane of the anus and is very painful and difficult to heal. (Dorland, 27th ed & Stedman, 25th ed) [MeSH]
MedDRA Code 10002153
MeSH ID D005401
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE)
Synonym
Anal fissure | Fissure anal | Fissure in ano | Chronic anal fissure | Anal tear | Fissure in Ano | Anal Fissure | Fissure, Anal | Anal Ulcer | Anal Ulcers | Ulcer, Anal | Ulcers, Anal
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00023Acetaminophen--
BADD_D00047Afatinib0.000112%
BADD_D00194Azacitidine0.000280%
BADD_D00195Azathioprine0.000783%
BADD_D00260Betamethasone--
BADD_D00284Bortezomib--
BADD_D00306Budesonide--
BADD_D00330Cabozantinib0.000246%
BADD_D00410Celecoxib--
BADD_D00471Ciprofloxacin--
BADD_D00589Dasatinib0.000492%
BADD_D00620Desoximetasone--
BADD_D00723Doxorubicin0.000168%
BADD_D00809Escitalopram--
BADD_D00858Everolimus0.000229%
BADD_D00898Finasteride0.000166%
BADD_D01022Gliclazide--
BADD_D01086Hydrocortisone--
BADD_D01096Hydromorphone--
BADD_D01213Isotretinoin0.025472%
BADD_D01250Lasofoxifene--
BADD_D01392Mercaptopurine--
BADD_D01397Mesalamine0.000183%
BADD_D01418Methotrexate--
BADD_D01433Methylprednisolone--
BADD_D01449Metronidazole--
BADD_D01498Morphine--
BADD_D01562Nicorandil--
BADD_D01567Nilotinib0.000112%
BADD_D01609Omacetaxine mepesuccinate--
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