Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Acute myeloid leukaemia
ADR ID BADD_A00078
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.01      Leukaemias
16.01.05      Leukaemias acute myeloid
16.01.05.001      Acute myeloid leukaemia
01      Blood and lymphatic system disorders
01.10      Leukaemias
01.10.05      Leukaemias acute myeloid
01.10.05.001      Acute myeloid leukaemia
Description Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES. [MeSH]
MedDRA Code 10000880
MeSH ID D015470
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Acute granulocytic leukaemia | Acute myeloblastic leukemia | Acute myeloid leukaemia | Acute myeloid leukaemia aggravat. | Acute myeloid leukaemia aggravated | Acute myeloid leukaemia NOS | Acute myeloid leukaemia with minimal differentiation | Acute myeloid leukemia | Acute myeloid leukemia with minimal differentiation | Acute myeloid leukemia without mention of remission | AML | Leukaemia undifferentiated | Leukemia myeloblastic acute | Leukemia undifferentiated | Myeloid leukaemia, acute | Myeloid leukemia, acute | Non-lymphoblastic leukaemia acute | Non-lymphoblastic leukaemia NOS | Non-lymphoblastic leukemia acute | Non-lymphoblastic leukemia NOS | Acute myelocytic leukaemia | Acute myeloid leukemia aggravated | Acute myeloid leukemia NOS | Acute myeloblastic leukaemia | Acute myeloid leukaemia without mention of remission | Leukaemia myeloblastic acute | Acute granulocytic leukemia | Acute myelocytic leukemia | Treatment related acute myeloid leukemia | Treatment related acute myeloid leukaemia | AML progression | Acute myeloid leukemia progression | Acute myeloid leukaemia progression | Leukemia, Myeloid, Acute | Acute Myeloid Leukemia | Acute Myeloid Leukemias | Leukemias, Acute Myeloid | Myeloid Leukemias, Acute | ANLL | Leukemia, Acute Myelogenous | Leukemia, Acute Myeloid | Leukemia, Myeloblastic, Acute | Leukemia, Myelocytic, Acute | Leukemia, Myelogenous, Acute | Leukemia, Nonlymphoblastic, Acute | Leukemia, Nonlymphocytic, Acute | Myeloblastic Leukemia, Acute | Acute Myeloblastic Leukemia | Acute Myeloblastic Leukemias | Leukemia, Acute Myeloblastic | Leukemias, Acute Myeloblastic | Myeloblastic Leukemias, Acute | Myelocytic Leukemia, Acute | Acute Myelocytic Leukemia | Acute Myelocytic Leukemias | Leukemia, Acute Myelocytic | Leukemias, Acute Myelocytic | Myelocytic Leukemias, Acute | Myelogenous Leukemia, Acute | Myeloid Leukemia, Acute | Nonlymphoblastic Leukemia, Acute | Acute Nonlymphoblastic Leukemia | Acute Nonlymphoblastic Leukemias | Leukemia, Acute Nonlymphoblastic | Leukemias, Acute Nonlymphoblastic | Nonlymphoblastic Leukemias, Acute | Nonlymphocytic Leukemia, Acute | Acute Nonlymphocytic Leukemia | Acute Nonlymphocytic Leukemias | Leukemia, Acute Nonlymphocytic | Leukemias, Acute Nonlymphocytic | Nonlymphocytic Leukemias, Acute | Acute Myelogenous Leukemia | Acute Myelogenous Leukemias | Leukemias, Acute Myelogenous | Myelogenous Leukemias, Acute | Myeloid Leukemia, Acute, M1 | Leukemia, Myeloid, Acute, M1 | Acute Myeloid Leukemia without Maturation | Leukemia, Myeloid, Acute, M2 | Myeloid Leukemia, Acute, M2 | Acute Myeloid Leukemia with Maturation
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01110Hydroxyurea0.001567%
BADD_D01133Ifosfamide--
BADD_D01136Imatinib0.001455%
BADD_D01217Itraconazole0.002672%
BADD_D01253Lenalidomide0.025003%
BADD_D01257Letrozole0.000922%
BADD_D01376Melphalan0.000224%
BADD_D01381Mepact--
BADD_D01392Mercaptopurine0.002082%
BADD_D01480Mitoxantrone0.000112%
BADD_D01481Mitoxantrone hydrochloride--
BADD_D01549Nelarabine0.000112%
BADD_D01567Nilotinib0.000783%
BADD_D01601Olaparib0.003694%
BADD_D01633Oxaliplatin0.000392%
BADD_D01653Paclitaxel0.001063%
BADD_D01804Posaconazole0.014185%
BADD_D01814Pralatrexate0.000112%
BADD_D01831Prednisolone0.000140%
BADD_D01834Prednisone0.000098%
BADD_D01846Procarbazine--
BADD_D01847Procarbazine hydrochloride--
BADD_D01952Ritonavir--
BADD_D01978Ruxolitinib0.005078%
BADD_D01989Saquinavir mesylate--
BADD_D02058Sorafenib0.000672%
BADD_D02150Temozolomide0.000336%
BADD_D02153Teniposide--
BADD_D02192Thalidomide0.000844%
BADD_D02203Thiotepa--
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