Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Stavudine
Drug ID BADD_D02068
Description A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
Indications and Usage For the treatment of human immunovirus (HIV) infections.
Marketing Status approved; investigational
ATC Code J05AF04
DrugBank ID DB00649
KEGG ID D00445
MeSH ID D018119
PubChem ID 18283
TTD Drug ID D0Z8EX
NDC Product Code 65015-672; 65862-342; 68554-0015; 65862-263; 53104-0111; 65015-795; 68554-0045
UNII BO9LE4QFZF
Synonyms Stavudine | D4T | 2',3'-Didehydro-3'-deoxythymidine | 2',3' Didehydro 3' deoxythymidine | 2',3'-Didehydro-2',3'-dideoxythmidine | Zerit | BMY-27857 | BMY 27857 | BMY27857 | Stavudine, Monosodium Salt
Chemical Information
Molecular Formula C10H12N2O4
CAS Registry Number 3056-17-5
SMILES CC1=CN(C(=O)NC1=O)C2C=CC(O2)CO
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Fungal infection11.03.05.001---
Gastrointestinal disorder07.11.01.001---
Gastrointestinal pain07.01.05.005--
Guillain-Barre syndrome10.04.10.005; 11.07.01.001; 17.09.01.001--
Gynaecomastia05.05.02.003; 21.05.04.003--
Haematuria20.02.01.006; 21.10.01.018; 24.07.01.047--
Haemoglobin decreased13.01.05.003---
Headache17.14.01.001--
Hepatic failure09.01.03.002--
Hepatic function abnormal09.01.02.001---
Hepatic steatosis09.01.07.003; 14.08.04.005---
Hepatitis09.01.07.004---
Hepatitis B09.01.09.003; 11.05.28.003--
Hepatocellular injury09.01.07.008---
Hepatomegaly09.01.05.001---
Hepatotoxicity09.01.07.009; 12.03.01.008---
Hyperbilirubinaemia01.06.04.003; 09.01.01.003; 14.11.01.010---
Hypercholesterolaemia14.08.01.001---
Hyperglycaemia05.06.02.002; 14.06.02.002--
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hyperlactacidaemia14.01.01.0060.000565%-
Hypersensitivity10.01.03.003--
Hypertriglyceridaemia14.08.02.001--
Hypoaesthesia17.02.06.023; 23.03.03.081---
Influenza11.05.03.001; 22.07.02.001---
Injury12.01.08.004---
Insomnia17.15.03.002; 19.02.01.002--
Insulin resistance05.06.02.003; 14.06.02.003---
Jaundice01.06.04.004; 09.01.01.004; 23.03.03.030---
Lactic acidosis14.01.01.0020.000988%-
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ADReCS-Target
Drug Name ADR Term Target
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