Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Insulin resistance
ADR ID BADD_A02367
ADR Hierarchy
14      Metabolism and nutrition disorders
14.06      Glucose metabolism disorders (incl diabetes mellitus)
14.06.02      Hyperglycaemic conditions NEC
14.06.02.003      Insulin resistance
05      Endocrine disorders
05.06      Glucose metabolism disorders (incl diabetes mellitus)
05.06.02      Hyperglycaemic conditions NEC
05.06.02.003      Insulin resistance
Description Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS. [MeSH]
MedDRA Code 10022489
MeSH ID D007333
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Insulin resistance | Insulin Resistance | Resistance, Insulin | Insulin Sensitivity | Sensitivity, Insulin
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00008Abacavir--
BADD_D00136Amprenavir--
BADD_D00165Aripiprazole0.000079%
BADD_D00176Atazanavir--
BADD_D00511Clozapine0.001223%
BADD_D00586Darunavir--
BADD_D00623Dexamethasone0.000581%
BADD_D00749Efavirenz--
BADD_D00766Emtricitabine--
BADD_D00932Fluoxetine0.000020%
BADD_D00961Fosamprenavir calcium--
BADD_D01150Indinavir--
BADD_D01242Lamivudine--
BADD_D01401Metformin0.000051%
BADD_D01418Methotrexate0.000580%
BADD_D01550Nelfinavir mesylate--
BADD_D01557Nevirapine--
BADD_D01888Quetiapine0.000055%
BADD_D01951Risperidone0.000327%
BADD_D01989Saquinavir mesylate--
BADD_D02026Simvastatin0.000011%
BADD_D02047Sodium oxybate0.000268%
BADD_D02068Stavudine--
BADD_D02155Tenofovir disoproxil--
BADD_D02227Tipranavir disodium--
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ADReCS-Target
ADR Term Drug Name Target