Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Plasma cell myelomas
ADR ID BADD_A06747
ADR Hierarchy
01      Blood and lymphatic system disorders
01.14      Plasma cell neoplasms
01.14.02      Plasma cell myelomas
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.23      Plasma cell neoplasms
16.23.02      Plasma cell myelomas
Description A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY. [MeSH]
MedDRA Code 10074470
MeSH ID D009101
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Multiple Myeloma | Multiple Myelomas | Myelomas, Multiple | Myeloma, Multiple | Myeloma, Plasma-Cell | Myeloma, Plasma Cell | Myelomas, Plasma-Cell | Plasma-Cell Myeloma | Plasma-Cell Myelomas | Myelomatosis | Myelomatoses | Plasma Cell Myeloma | Cell Myeloma, Plasma | Cell Myelomas, Plasma | Myelomas, Plasma Cell | Plasma Cell Myelomas | Kahler Disease | Disease, Kahler | Myeloma-Multiple | Myeloma Multiple | Myeloma-Multiples
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00284Bortezomib0.076481%
BADD_D00367Carfilzomib0.015211%
BADD_D00497Clomiphene--
BADD_D00498Clomiphene citrate--
BADD_D00623Dexamethasone0.009808%
BADD_D00680Dimethyl fumarate0.000600%
BADD_D00723Doxorubicin0.000168%
BADD_D00757Eliglustat0.004312%
BADD_D01110Hydroxyurea0.000448%
BADD_D01119Ibrutinib0.000112%
BADD_D01136Imatinib0.000112%
BADD_D01223Ixazomib0.016162%
BADD_D01250Lasofoxifene--
BADD_D01253Lenalidomide0.978965%
BADD_D01376Melphalan0.000112%
BADD_D01506Muromonab-cd3--
BADD_D01662Pamidronic acid0.000126%
BADD_D01798Pomalidomide0.434750%
BADD_D01817Pramipexole--
BADD_D01818Pramipexole dihydrochloride--
BADD_D01834Prednisone0.000018%
BADD_D01858Propagermanium--
BADD_D01908Ramelteon0.003795%
BADD_D01950Risedronic acid--
BADD_D01978Ruxolitinib--
BADD_D02007Semaxanib--
BADD_D02105Tacrolimus0.000446%
BADD_D02165Teriflunomide0.000241%
BADD_D02192Thalidomide0.042243%
BADD_D02345Venetoclax0.002239%
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