Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Cytokine release syndrome
ADR ID BADD_A05078
ADR Hierarchy
10      Immune system disorders
10.02      Immune disorders NEC
10.02.01      Immune and associated conditions NEC
10.02.01.010      Cytokine release syndrome
Description A disorder characterized by fever, tachypnea, headache, tachycardia, hypotension, rash, and/or hypoxia caused by the release of cytokines. [CTCAE]
MedDRA Code 10052015
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Cytokine release syndrome
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00214Basiliximab--
BADD_D00230Bendamustine0.001007%
BADD_D00282Blinatumomab--
BADD_D00284Bortezomib0.000336%
BADD_D00364Carboplatin0.000112%
BADD_D00367Carfilzomib0.000224%
BADD_D00386Cefepime0.000049%
BADD_D00429Chlorambucil0.000112%
BADD_D00589Dasatinib0.000392%
BADD_D00623Dexamethasone0.001962%
BADD_D00759Eltrombopag0.000229%
BADD_D00912Fluconazole0.000045%
BADD_D00914Fludarabine0.002630%
BADD_D01110Hydroxyurea0.000112%
BADD_D01119Ibrutinib0.000168%
BADD_D01136Imatinib0.000224%
BADD_D01238Lacosamide0.001463%
BADD_D01265Levetiracetam0.001033%
BADD_D01318Lorazepam0.000031%
BADD_D01376Melphalan0.000112%
BADD_D01392Mercaptopurine0.001041%
BADD_D01393Meropenem0.000049%
BADD_D01433Methylprednisolone0.000048%
BADD_D01445Metoprolol0.000010%
BADD_D01506Muromonab-cd3--
BADD_D01596Ofatumumab--
BADD_D01633Oxaliplatin0.003806%
BADD_D01799Ponatinib0.000336%
BADD_D01834Prednisone0.000022%
BADD_D01858Propagermanium--
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ADReCS-Target
ADR Term Drug Name Target