Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Left ventricular dysfunction
ADR ID BADD_A04856
ADR Hierarchy
02      Cardiac disorders
02.04      Myocardial disorders
02.04.02      Myocardial disorders NEC
02.04.02.011      Left ventricular dysfunction
Description A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall. [MeSH]
MedDRA Code 10049694
MeSH ID D018487
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Post MI left ventricular dysfunction | Left ventricular dysfunction | Left ventricular systolic dysfunction | Left ventricular diastolic dysfunction | Ventricular Dysfunction, Left | Left Ventricular Dysfunction | Dysfunction, Left Ventricular | Dysfunctions, Left Ventricular | Left Ventricular Dysfunctions | Ventricular Dysfunctions, Left
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01445Metoprolol0.000007%
BADD_D01470Minocycline0.000118%
BADD_D01506Muromonab-cd3--
BADD_D01567Nilotinib0.000560%
BADD_D01599Olanzapine0.000947%
BADD_D01617Ondansetron0.000021%
BADD_D01629Osimertinib0.000470%
BADD_D01633Oxaliplatin0.000224%
BADD_D01653Paclitaxel0.000168%
BADD_D01679Paroxetine0.000043%
BADD_D01687Pazopanib0.000392%
BADD_D01688Pazopanib hydrochloride--
BADD_D01698Pegloticase--
BADD_D01734Perflutren-
BADD_D01744Pertuzumab--
BADD_D01786Pixantrone--
BADD_D01799Ponatinib--
BADD_D01834Prednisone--
BADD_D01858Propagermanium--
BADD_D01864Propofol0.000179%
BADD_D01909Ramipril0.000186%
BADD_D01915Ranolazine0.000284%
BADD_D01922Regorafenib0.000168%
BADD_D01951Risperidone0.000424%
BADD_D01970Rosiglitazone maleate--
BADD_D01971Rosuvastatin0.000038%
BADD_D02018Sildenafil0.000107%
BADD_D02058Sorafenib0.000358%
BADD_D02100Sunitinib0.000336%
BADD_D02105Tacrolimus0.000594%
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ADReCS-Target
ADR Term Drug Name Target