Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Ventricular fibrillation
ADR ID BADD_A04561
ADR Hierarchy
02      Cardiac disorders
02.03      Cardiac arrhythmias
02.03.04      Ventricular arrhythmias and cardiac arrest
02.03.04.008      Ventricular fibrillation
Description A disorder characterized by a dysrhythmia without discernible QRS complexes due to rapid repetitive excitation of myocardial fibers without coordinated contraction of the ventricles. [CTCAE] A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST. [MeSH]
MedDRA Code 10047290
MeSH ID D014693
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Fibrillation paroxysmal vent | Fibrillation ventricular | Paroxysmal ventricular fibrillation | Ventricular fibrillation | Ventricular fibrillation and flutter | Ventricular fibrillation paroxysm | Ventricular fibrillation paroxysmal | VF | Recurrent ventricular fibrillation | Ventricular Fibrillation | Fibrillation, Ventricular | Fibrillations, Ventricular | Ventricular Fibrillations
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01300Lisinopril0.000016%
BADD_D01322Losartan--
BADD_D01323Losartan potassium--
BADD_D01350Maprotiline--
BADD_D01397Mesalamine0.000183%
BADD_D01401Metformin0.000084%
BADD_D01405Methadone0.001989%
BADD_D01406Methadone hydrochloride--
BADD_D01428Methylergonovine--
BADD_D01433Methylprednisolone0.000048%
BADD_D01442Metoclopramide--
BADD_D01445Metoprolol0.000057%
BADD_D01449Metronidazole0.000066%
BADD_D01467Milrinone--
BADD_D01468Milrinone lactate--
BADD_D01477Misoprostol0.001233%
BADD_D01498Morphine--
BADD_D01502Moxifloxacin hydrochloride--
BADD_D01525Naloxone--
BADD_D01526Naloxone hydrochloride--
BADD_D01535Naratriptan--
BADD_D01557Nevirapine0.002652%
BADD_D01574Nitric oxide-
BADD_D01588Nortriptyline--
BADD_D01599Olanzapine0.000842%
BADD_D01617Ondansetron0.000021%
BADD_D01629Osimertinib0.000168%
BADD_D01633Oxaliplatin0.000280%
BADD_D01637Oxcarbazepine0.000170%
BADD_D01653Paclitaxel0.000336%
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ADReCS-Target
ADR Term Drug Name Target