Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Methylergonovine
Drug ID BADD_D01428
Description A homolog of ergonovine containing one more CH2 group. (Merck Index, 11th ed)
Indications and Usage For the prevention and control of excessive bleeding following vaginal childbirth
Marketing Status approved
ATC Code G02AB01
DrugBank ID DB00353
KEGG ID D00680; D08207
MeSH ID D008755
PubChem ID 8226
TTD Drug ID D05AHE
NDC Product Code 69238-1605
UNII W53L6FE61V
Synonyms Methylergonovine | Methylergometrine | Methylergobasin | Methylergometrin | Methylergonovine Maleate | Methylergometrine Maleate | Methergine | Méthergin | Methergin
Chemical Information
Molecular Formula C20H25N3O2
CAS Registry Number 113-42-8
SMILES CCC(CO)NC(=O)C1CN(C2CC3=CNC4=CC=CC(=C34)C2=C1)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.0020.002243%
Acute myocardial infarction02.02.02.001; 24.04.04.001---
Agitation17.02.05.012; 19.06.02.0010.002243%
Anaphylactic shock10.01.07.002; 24.06.02.004---
Angina pectoris02.02.02.002; 24.04.04.002--
Apnoea22.02.01.0010.003365%
Areflexia17.02.01.0010.002243%-
Arterial spasm24.04.02.011---
Arteriospasm coronary02.02.02.005; 12.02.01.031; 24.04.04.0050.002243%-
Atrioventricular block02.03.01.002---
Bradycardia02.03.02.0020.003365%-
Bronchospasm10.01.03.012; 22.03.01.0040.003365%
Cerebrovascular accident17.08.01.007; 24.03.05.001--
Chest pain02.02.02.011; 08.01.08.002; 22.12.02.003---
Crying08.01.03.005; 12.02.11.001; 17.02.05.013; 19.04.02.0020.002243%-
Cyanosis02.11.04.004; 22.02.02.007; 23.06.04.005; 24.03.01.0070.003365%
Dermatitis23.03.04.002---
Diarrhoea07.02.01.0010.002243%
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.0070.003365%
Drug ineffective08.06.01.0060.002243%-
Dyspnoea02.11.05.003; 22.02.01.0040.004486%
Face oedema08.01.07.003; 10.01.05.002; 23.04.01.0040.002243%
Gastrointestinal pain07.01.05.005--
Haematuria20.02.01.006; 21.10.01.018; 24.07.01.047--
Hallucination19.10.04.003--
Headache17.14.01.0010.005608%
Hyperaesthesia17.02.06.004; 23.03.03.0800.002243%-
Hypercapnia14.01.04.001; 22.02.02.0020.003365%-
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hypertension24.08.02.0010.002243%
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