Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Splenomegaly
ADR ID BADD_A04138
ADR Hierarchy
01      Blood and lymphatic system disorders
01.09      Spleen, lymphatic and reticuloendothelial system disorders
01.09.02      Spleen disorders
01.09.02.001      Splenomegaly
Description Enlargement of the spleen. [MeSH]
MedDRA Code 10041660
MeSH ID D013163
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Chronic congestive splenomegaly | Spleen dullness enlarged | Spleen enlarged | Splenomegaly | Megalosplenia | Hypersplenotrophy | Enlarged Spleen | Spleen, Enlarged
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01867Propranolol0.000053%
BADD_D01869Propylthiouracil--
BADD_D01880Pyrazinamide--
BADD_D01905Raltegravir0.001648%
BADD_D01933Ribavirin0.037580%
BADD_D01951Risperidone0.000303%
BADD_D01971Rosuvastatin0.000017%
BADD_D01978Ruxolitinib0.025334%
BADD_D01989Saquinavir mesylate--
BADD_D02007Semaxanib--
BADD_D02026Simvastatin0.000007%
BADD_D02029Sitagliptin0.000080%
BADD_D02093Sulfasalazine0.000455%
BADD_D02105Tacrolimus0.001337%
BADD_D02154Tenofovir0.002908%
BADD_D02192Thalidomide0.000482%
BADD_D02199Thioguanine--
BADD_D02312Ulipristal--
BADD_D02326Valganciclovir--
BADD_D02329Valproic acid0.000100%
BADD_D02337Varenicline--
BADD_D02338Varenicline tartrate--
BADD_D02345Venetoclax0.001388%
BADD_D02369Voriconazole--
BADD_D02373Warfarin0.000112%
BADD_D02375Water--
BADD_D02383Zidovudine--
BADD_D02468Cannabidiol0.000125%
BADD_D02480Alectinib0.000112%
BADD_D02482Acalabrutinib0.000224%
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