Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Stavudine
Drug ID BADD_D02068
Description A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
Indications and Usage For the treatment of human immunovirus (HIV) infections.
Marketing Status approved; investigational
ATC Code J05AF04
DrugBank ID DB00649
KEGG ID D00445
MeSH ID D018119
PubChem ID 18283
TTD Drug ID D0Z8EX
NDC Product Code 65015-672; 65862-342; 68554-0015; 65862-263; 53104-0111; 65015-795; 68554-0045
UNII BO9LE4QFZF
Synonyms Stavudine | D4T | 2',3'-Didehydro-3'-deoxythymidine | 2',3' Didehydro 3' deoxythymidine | 2',3'-Didehydro-2',3'-dideoxythmidine | Zerit | BMY-27857 | BMY 27857 | BMY27857 | Stavudine, Monosodium Salt
Chemical Information
Molecular Formula C10H12N2O4
CAS Registry Number 3056-17-5
SMILES CC1=CN(C(=O)NC1=O)C2C=CC(O2)CO
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Abnormal dreams17.15.02.001; 19.02.03.001---
Acne23.02.01.001---
Anaemia01.03.02.001--
Anxiety19.06.02.002--
Arthralgia15.01.02.001--
Asthenia08.01.01.001---
Back pain15.03.04.005--
Blood triglycerides increased13.12.03.001---
Body temperature increased13.15.01.001---
Breast enlargement21.05.04.001---
Bronchitis11.01.09.001; 22.07.01.001--
Chills08.01.09.001; 15.05.03.016--
Conjunctivitis06.04.01.002; 11.01.06.012--
Constipation07.02.02.001--
Cough22.02.03.001--
Depression19.15.01.001--
Dermatitis23.03.04.002---
Diabetes mellitus05.06.01.001; 14.06.01.0010.000282%-
Diarrhoea07.02.01.001--
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dry mouth07.06.01.002--
Dry skin23.03.03.001--
Dysgeusia07.14.03.001; 17.02.07.003--
Dyspepsia07.01.02.001--
Dysuria20.02.02.002--
Endocrine disorder05.09.01.001---
Eructation07.01.02.003--
Fatigue08.01.01.002--
Flatulence07.01.04.002--
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ADReCS-Target
Drug Name ADR Term Target
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