Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Corneal perforation
ADR ID BADD_A01089
ADR Hierarchy
06      Eye disorders
06.06      Anterior eye structural change, deposit and degeneration
06.06.03      Corneal structural change, deposit and degeneration
06.06.03.006      Corneal perforation
12      Injury, poisoning and procedural complications
12.01      Injuries NEC
12.01.04      Eye injuries NEC
12.01.04.003      Corneal perforation
Description A puncture or hole through the CORNEAL STROMA resulting from various diseases or trauma. [MeSH]
MedDRA Code 10011039
MeSH ID D057112
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Corneal perforation | Perforation corneal | Corneal Perforation | Corneal Perforations | Perforation, Corneal | Perforations, Corneal
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00039Acyclovir0.000107%
BADD_D00300Bromfenac--
BADD_D00301Bromfenac sodium--
BADD_D00623Dexamethasone0.000218%
BADD_D00653Diclofenac0.000026%
BADD_D00800Erlotinib0.000168%
BADD_D00931Fluorouracil0.000184%
BADD_D01006Gatifloxacin--
BADD_D01232Ketorolac--
BADD_D01233Ketorolac tromethamine--
BADD_D01555Nepafenac0.000588%
BADD_D01616Onabotulinumtoxina--
BADD_D01654Palbociclib0.000112%
BADD_D01829Prednefrin--
BADD_D01832Prednisolone acetate0.003238%
BADD_D01862Proparacaine0.000107%
BADD_D02150Temozolomide0.000112%
BADD_D02236Tofacitinib0.000241%
BADD_D02367Voltaren--
BADD_D02369Voriconazole0.005809%
BADD_D02447Flavin mononucleotide-
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